Acute kidney injury associated with Plasmodium malariae infection

被引:23
作者
Badiane, Aida S. [1 ,4 ]
Diongue, Khadim [1 ]
Diallo, Seydou [1 ]
Ndongo, Aliou A. [3 ]
Diedhiou, Cyrille K. [2 ]
Deme, Awa B. [2 ]
Ma, Diallo [1 ]
Ndiaye, Mouhamadou [1 ,4 ]
Seck, Mame C. [1 ,4 ]
Dieng, Therese [4 ]
Ndir, Omar [1 ,4 ]
Mboup, Souleymane [2 ]
Ndiaye, Daouda [1 ,4 ]
机构
[1] LeDantec Hosp, Lab Parasitol Mycol, Dakar, Senegal
[2] LeDantec Hosp, Lab Bacteriol Virol, Malaria Unit, Dakar, Senegal
[3] LeDantec Hosp, Dakar, Senegal
[4] Cheikh Anta Diop Univ Dakar, Lab Parasitol Mycol, Dakar, Senegal
关键词
Plasmodium malariae; Kidney injury; Senegal; NEPHROTIC SYNDROME; NIGERIAN CHILDREN; PARASITEMIA; AREA;
D O I
10.1186/1475-2875-13-226
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
According to current estimates, Plasmodium malariae is not very common in Senegal, as more than 98% of malaria cases are suspected to be due to Plasmodium falciparum. However, it is possible that other malarial species are being under-reported or misdiagnosed. This is a report of a case of P. malariae in a 30-year-old man previously hospitalized with acute kidney injury after treatment with quinine and re-hospitalized three months later. He was diagnosed with renal cortical necrosis post malaria treatment. Plasmodium malariae was identified with light microscope and confirmed using species-specific small-subunit rRNA (ssrRNA) amplification. The patient was treated for malaria with intravenous quinine for seven days, followed by three days of oral treatment; the bacterial infection was treated using ceftriaxone during the first hospitalization and ciprofloxacin associated with ceftriaxone the second time. He also had four rounds of dialysis after which he partially recovered the renal function. Given the complications that can be caused by P. malariae infection, it should be systematically looked for, even if the predominant species is P. falciparum in Senegal.
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页数:5
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