Direct Conversion of Alcohols to Acetals and H2 Catalyzed by an Acridine-Based Ruthenium Pincer Complex

被引：228
作者：
Gunanathan, Chidambaram [1 ]
Shimon, Linda J. W. [2 ]
Milstein, David [1 ]
机构：
[1] Weizmann Inst Sci, Dept Organ Chem, IL-76100 Rehovot, Israel
[2] Weizmann Inst Sci, Unit Chem Res Support, IL-76100 Rehovot, Israel
来源：
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2009年 / 131卷 / 09期
关键词：
ALDEHYDES; ESTERS; OXIDATION; EFFICIENT;
D O I：
10.1021/ja808893g
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The crystallographically characterized ruthenium complex RuHCl(A-'Pr-PNP)(CO) (1) [A-'Pr-PNP = 4,5-bis-(diisopropylphosphinomethyl)acridine], which bears a nonplanar acridine moiety, catalyzes in a neutral medium the transformation of primary alcohols to the corresponding acetals with the liberation of H-2. In the presence of base, complex I catalyzes the dehydrogenative coupling of alcohols to form esters. Acetal formation may involve hemiacetal dehydration to form an enol ether followed by alcohol addition to the double bond.
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收藏
页码：3146 / +
页数：3
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