EPIMIC: A Simple Homemade Computer Program for Real-Time EPIdemiological Surveillance and Alert Based on MICrobiological Data

被引:16
作者
Colson, Philippe [1 ,2 ]
Rolain, Jean-Marc [1 ,2 ]
Abat, Cedric [2 ]
Charrel, Remi [1 ,3 ]
Fournier, Pierre-Edouard [1 ,2 ]
Raoult, Didier [1 ,2 ]
机构
[1] CHU Timone, Assistance Publ Hop Marseille, Inst Hosp Univ IHU Mediterranee Infect, Pole Malad Infect & Trop Clin & Biol,Federat Bact, F-13385 Marseille 05, France
[2] Aix Marseille Univ, URMITE, INSERM, UM 63,CNRS 7278,IRD,3R198,U1095, F-13385 Marseille 05, France
[3] Aix Marseille Univ, IRD French Inst Res Dev, EHESP French Sch Publ Hlth, EPV UMR Emergence Pathol Virales D190, F-13385 Marseille, France
关键词
MARSEILLES; INFECTIONS; HOSPITALS; ENGLAND; WALES; OUTBREAK; DISEASE; BURDEN; FRANCE; TRENDS;
D O I
10.1371/journal.pone.0144178
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Background and Aims Infectious diseases (IDs) are major causes of morbidity and mortality and their surveillance is critical. In 2002, we implemented a simple and versatile homemade tool, named EPIMIC, for the real-time systematic automated surveillance of IDs at Marseille university hospitals, based on the data from our clinical microbiology laboratory, including clinical samples, tests and diagnoses. Methods This tool was specifically designed to detect abnormal events as IDs are rarely predicted and modeled. EPIMIC operates using Microsoft Excel software and requires no particular computer skills or resources. An abnormal event corresponds to an increase above, or a decrease below threshold values calculated based on the mean of historical data plus or minus 2 standard deviations, respectively. Results Between November 2002 and October 2013 (11 years), 293 items were surveyed weekly, including 38 clinical samples, 86 pathogens, 79 diagnosis tests, and 39 antibacterial resistance patterns. The mean duration of surveillance was 7.6 years (range, 1 month-10.9 years). A total of 108,427 Microsoft Excel file cells were filled with counts of clinical samples, and 110,017 cells were filled with counts of diagnoses. A total of 1,390,689 samples were analyzed. Among them, 172,180 were found to be positive for a pathogen. EPIMIC generated a mean number of 0.5 alert/week on abnormal events. Conclusions EPIMIC proved to be efficient for real-time automated laboratory-based surveillance and alerting at our university hospital clinical microbiology laboratory-scale. It is freely downloadable from the following URL: http://www.mediterranee-infection.com/article.php?larub=157&titre=bulletin-epidemiologique (last accessed: 20/11/2015).
引用
收藏
页数:13
相关论文
共 32 条
[1]   Increasing burden of urinary tract infections due to intrinsic colistin-resistant bacteria in hospitals in Marseille, France [J].
Abat, Cedric ;
Desboves, Guillaume ;
Olaitan, Abiola Olumuyiwa ;
Chaudet, Herve ;
Roattino, Nicole ;
Fournier, Pierre-Edouard ;
Colson, Philippe ;
Raoult, Didier ;
Rolain, Jean-Marc .
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2015, 45 (02) :144-150
[2]   Increased incidence of acute parvovirus B19 infections in Marseille, France, in 2012 compared with the 2002-2011 period [J].
Aherfi, S. ;
Ninove, L. ;
Zandotti, C. ;
Crepey, P. ;
Richet, H. ;
Nougairede, A. ;
de Lamballerie, X. ;
Charrel, R. N. .
CLINICAL MICROBIOLOGY AND INFECTION, 2014, 20 (03) :O176-O181
[3]   Seasonal variation in Klebsiella pneumoniae bloodstream infection on 4 continents [J].
Anderson, Deverick J. ;
Richet, Herve ;
Chen, Luke F. ;
Spelman, Denis W. ;
Hung, Yi-Ju ;
Huang, Andrew T. ;
Sexton, Daniel J. ;
Raoult, Didier .
JOURNAL OF INFECTIOUS DISEASES, 2008, 197 (05) :752-756
[4]  
[Anonymous], 2013, World health statistics 2013: A wealth of information on global public health
[5]  
[Anonymous], 1981, Multiple Morbidity Weekly Report, V30, P1
[6]  
Colson P, 2013, Euro Surveill, V18, P4
[7]  
Colson P, 2013, EUROSURVEILLANCE, V18, P18
[8]   Autochthonous Infections with Hepatitis E Virus Genotype 4, France [J].
Colson, Philippe ;
Romanet, Pauline ;
Moal, Valerie ;
Borentain, Patrick ;
Purgus, Raj ;
Benezech, Alban ;
Motte, Anne ;
Gerolami, Rene .
EMERGING INFECTIOUS DISEASES, 2012, 18 (08) :1361-1364
[9]  
Dab W, 1998, REV EPIDEMIOL SANTE, V46, P249
[10]   Automated Biosurveillance Data from England and Wales, 1991-2011 [J].
Enki, Doyo G. ;
Noufaily, Angela ;
Garthwaite, Paul H. ;
Andrews, Nick J. ;
Charlett, Andre ;
Lane, Chris ;
Farrington, C. Paddy .
EMERGING INFECTIOUS DISEASES, 2013, 19 (01) :35-42