Distraction from randomization in diagnostic research

被引：22

作者：

Biesheuvel, Cornelis J. ^{[1
]}

Grobbee, Diederick E. ^{[1
]}

Moons, Karel G. M. ^{[1
]}

机构：

[1] Univ Utrecht, Med Ctr, Julius Ctr Hlth Sci & Primary Care, NL-3508 TC Utrecht, Netherlands

来源：

ANNALS OF EPIDEMIOLOGY | 2006年 / 16卷 / 07期

关键词：

diagnostic research; study design; randomization;

D O I：

10.1016/j.annepidem.2005.10.004

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

The ultimate goal of medical care, including diagnostic testing, is to improve patient outcome. Accordingly, it has been advocated widely that when establishing a test's diagnostic accuracy, the impact of the test on patient outcome subsequently must be quantified. When studying patient outcome in medical research, the use of randomized comparisons comes into perspective. In our view, randomized studies often are not necessary to validly estimate the effect of the diagnostic test on patient outcome. Results of cross-sectional diagnostic studies, combined with results from therapeutic studies, often will suffice.

引用

页码：540 / 544

页数：5

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