Fe(OTf)3 Catalyzed Annulation of 2,3-Disubstituted Indoles with Aziridines

被引：18
|
作者：
Liu, Hua [1 ]
Zheng, Chao [1 ]
You, Shu-Li [1 ]
机构：
[1] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China
来源：
CHINESE JOURNAL OF CHEMISTRY | 2014年 / 32卷 / 08期
关键词：
annulation; indole; aziridine; Lewis acid; catalysis; ALLYLIC DEAROMATIZATION REACTION; FORMAL 3+2 CYCLOADDITION; CARBON BOND-CLEAVAGE; ENANTIOSELECTIVE SYNTHESIS; CASCADE DEAROMATIZATION; CYCLOPENTANNULATION; PYRROLOINDOLINES; CYCLIZATION; TRYPTOPHOLS; ALKALOIDS;
D O I：
10.1002/cjoc.201400178
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A Fe(OTf)(3) catalyzed [3+2] annulation reaction between 2,3-disubstituted indoles and N-Ts aziridines is described herein. A series of hexahydropyrrolo[3,4-b]indole derivatives bearing two consecutive quaternary carboncenters can be generated efficiently. The reaction features cheap catalyst, mild conditions and operational simplicity.
引用
收藏
页码：709 / 714
页数：6
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