Fe(OTf)3 Catalyzed Annulation of 2,3-Disubstituted Indoles with Aziridines

被引：18

作者：

Liu, Hua ^{[1
]}

Zheng, Chao ^{[1
]}

You, Shu-Li ^{[1
]}

机构：

[1] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China

来源：

CHINESE JOURNAL OF CHEMISTRY | 2014年 / 32卷 / 08期

关键词：

annulation; indole; aziridine; Lewis acid; catalysis; ALLYLIC DEAROMATIZATION REACTION; FORMAL 3+2 CYCLOADDITION; CARBON BOND-CLEAVAGE; ENANTIOSELECTIVE SYNTHESIS; CASCADE DEAROMATIZATION; CYCLOPENTANNULATION; PYRROLOINDOLINES; CYCLIZATION; TRYPTOPHOLS; ALKALOIDS;

D O I：

10.1002/cjoc.201400178

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A Fe(OTf)(3) catalyzed [3+2] annulation reaction between 2,3-disubstituted indoles and N-Ts aziridines is described herein. A series of hexahydropyrrolo[3,4-b]indole derivatives bearing two consecutive quaternary carboncenters can be generated efficiently. The reaction features cheap catalyst, mild conditions and operational simplicity.

引用

页码：709 / 714

页数：6

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