Regulation of Escherichia coli cell division genes ftsA and ftsZ by the two-component system rcsC-rcsB

被引：89

作者：

Carballès, F ^{[1
]}

Bertrand, C ^{[1
]}

Bouché, JP ^{[1
]}

Cam, K ^{[1
]}

机构：

[1] CNRS, Lab Microbiol & Genet Mol, F-31062 Toulouse, France

来源：

MOLECULAR MICROBIOLOGY | 1999年 / 34卷 / 03期

关键词：

D O I：

10.1046/j.1365-2958.1999.01605.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Genes rcsC and rcsB form a two-component system in which rcsC encodes the sensor element and rcsB the regulator. In Escherichia coli, the system positively regulates the expression of the capsule operon, cps, and of the cell division gene ftsZ. We report the identification of the promoter and of the sequences required for rcsB-dependent stimulation of ftsZ expression. The promoter, ftsA1p, located in the ftsQ coding sequence, co-regulates ftsA and ftsZ. The sequences required for rcsB activity are immediately adjacent to this promoter.

引用

页码：442 / 450

页数：9

共 35 条

[1] DIVISION GENES IN ESCHERICHIA-COLI ARE EXPRESSED COORDINATELY TO CELL SEPTUM REQUIREMENTS BY GEARBOX PROMOTERS [J].

ALDEA, M ;

GARRIDO, T ;

PLA, J ;

VICENTE, M .

EMBO JOURNAL, 1990, 9 (11) :3787-3794

[2] The ftsQ1p gearbox promoter of Escherichia coli is a major sigma S-dependent promoter in the ddlB-ftsA region [J].

Ballesteros, M ;

Kusano, S ;

Ishihama, A ;

Vicente, M .

MOLECULAR MICROBIOLOGY, 1998, 30 (02) :419-430

[3] Roles of FtsA and FtsZ in activation of division sites [J].

Begg, K ;

Nikolaichik, Y ;

Crossland, N ;

Donachie, WD .

JOURNAL OF BACTERIOLOGY, 1998, 180 (04) :881-884

[4] FTSZ RING STRUCTURE ASSOCIATED WITH DIVISION IN ESCHERICHIA-COLI [J].

BI, E ;

LUTKENHAUS, J .

NATURE, 1991, 354 (6349) :161-164

[5] RNase E processing of essential cell division genes mRNA in Escherichia coli [J].

Cam, K ;

Rome, G ;

Krisch, HM ;

Bouche, JP .

NUCLEIC ACIDS RESEARCH, 1996, 24 (15) :3065-3070

[6] Point mutations in the transmembrane domain of DjlA, a membrane-linked DnaJ-like protein, abolish its function in promoting colanic acid production via the Rcs signal transduction pathway [J].

Clarke, DJ ;

Holland, IB ;

Jacq, A .

MOLECULAR MICROBIOLOGY, 1997, 25 (05) :933-944

[7] PLASMID PSC101 HARBORS A RECOMBINATION SITE, PSI, WHICH IS ABLE TO RESOLVE PLASMID MULTIMERS AND TO SUBSTITUTE FOR THE ANALOGOUS CHROMOSOMAL ESCHERICHIA-COLI SITE DIF [J].

CORNET, F ;

MORTIER, I ;

PATTE, J ;

LOUARN, JM .

JOURNAL OF BACTERIOLOGY, 1994, 176 (11) :3188-3195

[8] THE PROPER RATIO OF FTSZ TO FTSA IS REQUIRED FOR CELL-DIVISION TO OCCUR IN ESCHERICHIA-COLI [J].

DAI, K ;

LUTKENHAUS, J .

JOURNAL OF BACTERIOLOGY, 1992, 174 (19) :6145-6151

[9] THE ESSENTIAL BACTERIAL CELL-DIVISION PROTEIN FTSZ IS A GTPASE [J].

DEBOER, P ;

CROSSLEY, R ;

ROTHFIELD, L .

NATURE, 1992, 359 (6392) :254-256

[10] ANTISENSE TRANSCRIPTION OF THE FTSZ-FTSA GENE JUNCTION INHIBITS CELL-DIVISION IN ESCHERICHIA-COLI [J].

DEWAR, SJ ;

DONACHIE, WD .

JOURNAL OF BACTERIOLOGY, 1993, 175 (21) :7097-7101

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