Genetic epidemiology - Juvenile idiopathic arthritis genetics - What's new? What's next?

被引：25

作者：

Thomson, W ^{[1
]}

Donn, R ^{[1
]}

机构：

[1] Univ Manchester, Arthritis Res Campaign Epidemiol Unit, Sch Epidemiol & Hlth Sci, Manchester M13 9PT, Lancs, England

来源：

ARTHRITIS RESEARCH | 2002年 / 4卷 / 05期

关键词：

candidate genes; cytokines; genetics; juvenile idiopathic arthritis;

D O I：

10.1186/ar591

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Studies have established the magnitude of the genetic basis of juvenile idiopathic arthritis (JIA). JIA is a complex genetic condition and the genes that influence susceptibility are actively being sought. A candidate gene approach is being used by several groups. MHC-, cytokine- and T-cell-related genes have all been positively associated with JIA. Here we review some of the latest genetic data, and discuss ways in which JIA genetic research might proceed.

引用

页码：302 / 306

页数：5

共 41 条

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