Genetic epidemiology - Juvenile idiopathic arthritis genetics - What's new? What's next?

被引：25
作者：
Thomson, W [1 ]
Donn, R [1 ]
机构：
[1] Univ Manchester, Arthritis Res Campaign Epidemiol Unit, Sch Epidemiol & Hlth Sci, Manchester M13 9PT, Lancs, England
来源：
ARTHRITIS RESEARCH | 2002年 / 4卷 / 05期
关键词：
candidate genes; cytokines; genetics; juvenile idiopathic arthritis;
D O I：
10.1186/ar591
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Studies have established the magnitude of the genetic basis of juvenile idiopathic arthritis (JIA). JIA is a complex genetic condition and the genes that influence susceptibility are actively being sought. A candidate gene approach is being used by several groups. MHC-, cytokine- and T-cell-related genes have all been positively associated with JIA. Here we review some of the latest genetic data, and discuss ways in which JIA genetic research might proceed.
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收藏
页码：302 / 306
页数：5
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