Microdose computed tomographic cardiac angiography in normal cats

被引:6
作者
Rodriguez, Kiira T. [1 ]
O'Brien, Mauria A. [1 ]
Hartman, Susan K. [1 ]
Mulherin, Allison C. [1 ]
McReynolds, Casie J. [1 ]
McMichael, Maureen [1 ]
Rapoport, Gregg [2 ]
O'Brien, Robert T. [1 ]
机构
[1] Univ Illinois, Dept Vet Clin Med, Urbana, IL 61802 USA
[2] Univ Georgia, Dept Small Anim Med & Surg, Athens, GA 30602 USA
关键词
Feline; Heart; CT; Contrast; CONTRAST-INDUCED NEPHROPATHY; LEFT-VENTRICULAR FUNCTION; DISEASE; ECHOCARDIOGRAPHY; DOGS;
D O I
10.1016/j.jvc.2013.12.004
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
Objectives: To determine if microdose contrast-enhanced multi-detector computed tomographic angiography (MDCTA) allows characterization of cardiac chambers in lightly sedated normal cats. Animals: Seven healthy domestic cats. Methods: Lightly sedated normal cats were imaged pre-contrast and with microdose (0.22 ml/kg of non-ionic iodinated contrast medium, 300 mg l/ml) triple-phase MDCTA in a motion restriction device. Results: On pre-contrast images, the aorta (median: 52.43 Hounsfield units [HU], range 27.35-76.74 HU) was outlined by significantly (p = 0.015) lower attenuating periaortic fat (-66.16 HU, -42.62 to -92.77 HU). On post-contrast images, median peak contrast enhancement in the right ventricle (111.77 HU, 36.09-141.60 HU) was achieved in 3.1 s (range 2.9-7.3 s), in the aorta (149.30 HU, 99.43-319.60 HU) and left atrium (180.83 HU, 88.53-266.84 HU) in 6.4 s (range 5.6-7.7 s) and in the left ventricle (147.89 HU, 57.23-245.77 HU) in 7.10 s (range 6.2-11.2 s). Significantly higher attenuation was measured between all chambers and walls, the right ventricular lumen and interventricular septum (median ratio 53.78 HU, range 0.21-83.20 HU), left ventricular lumen and left ventricular free wall (89.32 HU, 38.81-185.95 HU) and aorta and periaortic fat (190.43 HU, 143.22-425.44 HU) on post-contrast images. Conclusions: Sufficient biological contrast is available on survey CT to discriminate between the aorta and the left atrium, and microdose MDCTA provides sufficient contrast enhancement for adequate visualization of the heart chambers in normal cats. (C) 2014 Elsevier B.V. All rights reserved.
引用
收藏
页码:19 / 25
页数:7
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