IMPROVEMENTS IN HIP OSTEOARTHRITIS WITH LAVAGE, TRIAMCINOLONE AND HYLAN G-F20

被引:7
作者
De Rezende, Marcia Uchoa [1 ,3 ]
Campos Gurgel, Henrique Melo [1 ,3 ]
Ocampos, Guilherme Pereira [1 ,3 ]
De Campos, Gustavo Constantino [2 ,3 ]
Frucchi, Renato [1 ,3 ]
Pailo, Alexandre Felicio [1 ,3 ]
Pasqualin, Thiago [1 ,3 ]
Negreiros Vicente, Jose Ricardo [1 ,3 ]
De Camargo, Olavo Pires [1 ,3 ]
机构
[1] Univ Sao Paulo, Hosp Clin, Med Sch, Inst Orthoped & Traumatol, Sao Paulo, SP, Brazil
[2] Univ Estadual Campinas, Campinas, SP, Brazil
[3] Univ Sao Paulo, Hosp Clin, Med Sch, Osteometab Dis Grp,Inst Orthoped & Traumatol, Sao Paulo, Brazil
来源
ACTA ORTOPEDICA BRASILEIRA | 2020年 / 28卷 / 06期
关键词
Hyaluronic Acid; Viscosupplementation; Triamcinolone; Osteoarthritis; Hip; Randomized Controlled Trial; Minimal Clinically Important Difference; KNEE OSTEOARTHRITIS; INJECTIONS; ULTRASOUND; EFFICACY; TRIAL; CD44;
D O I
10.1590/1413-785220202806240075
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
Objective: To verify whether the use of Hylan G-F20 improves saline lavage and triamcinolone injection results in the treatment of hip osteoarthritis (HOA). Methods: 82 patients with HOA categorized as grades II and III severity, according to Kellgren and Lawrence criteria, were randomized into the groups: lavage and triamcinolone (G0); lavage, triamcinolone, and 2 mL of hylan G-F20 (01); lavage, triamcinolone, and 4mL of hylan G-F20 (02); lavage, triamcinolone, and 6mL of hylan G-F20 (03). The VAS, range of motion (ROM), WOMAC, and Lequesne questionnaires were administered at baseline, one, three, six, and twelve months post-injection. Results: All groups showed clinically relevant improvements (> 20%) between baseline and first month post-injection, maintaining subjective results throughout the study period (p < 0.001). We found no differences between groups in any subjective evaluations (p > 0.05, for all). G2 and G3 obtained improved flexion results up to a year (p = 0.028). Hylan groups presented an improved external rotation since the first postoperative month and maintained the results up to a year (01, p = 0.041; G2, p = 0.007), whereas G0 showed no improvement (p = 0.336). Conclusion: Hip lavage and triamcinolone injection, with or without the use of hylan, improves pain, function, and quality of life up to a year in HOA. Hylan may improve ROM up to one year.
引用
收藏
页码:280 / 286
页数:7
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