Genotoxic effect of polycyclic aromatic hydrocarbons in the metropolitan area of Porto Alegre, Brazil, evaluated by Helix aspersa (Muller, 1774)

被引：29

作者：

Ianistcki, M. ^{[1
]}

Dallarosa, J. ^{[2
]}

Sauer, C.

Teixeira, C. E.

da Silva, J. ^{[1
]}

机构：

[1] Univ Luterana Brasil, Dept Biol, Lab Genet Toxicol, BR-92425900 Canoas, RS, Brazil

[2] Univ Fed Rio Grande do Sul, Ecol Lab, Porto Alegre, RS, Brazil

来源：

ENVIRONMENTAL POLLUTION | 2009年 / 157卷 / 07期

关键词：

Particulate matter; Traffic density; PAH; Genotoxicity; Helix aspersa; Comet assay; PARTICULATE MATTER; LUNG-CANCER; COMET ASSAY; URBAN AIR; EXPOSURE; SIZE;

D O I：

10.1016/j.envpol.2009.02.025

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

The purpose of this study was to biomonitor metropolitan areas of Porto Alegre (Brazil) for PAHs associated with atmospheric particles and check their effects on the DNA of the land mollusk Helix aspersa. The sampling sites are located in an urban area with heavy traffic: (i) Canoas, (ii) Sapucaia do Sul, and (iii) FIERGS/Porto Alegre. The samples were collected during a continuous period of 24 hours during 15 days using Stacked Filter Units (SFU) on polycarbonate filters (two separated size fractions: PM10-2.5 and PM<2.5). The concentrations of 16 major PAHs were determined according to EPA. Comet assay on H. aspersa hemolymph cells was chosen for genotoxicity evaluation. This evaluation shows that, in general, the smaller PM-size fractions (PM<2.5) have the highest genotoxicity and contain higher concentrations of extractable organic matter. In addition, associations between chemical characteristics and PM carcinogenicity tend to be stronger for the smaller PM-size fractions. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：2037 / 2042

页数：6

共 32 条

[1]

[Anonymous], 1999, TO13A USEPA

[2]

CLAXTON LD, 2007, MUTAT RES, V1, P36

[3]

Collins A, 1997, ENVIRON MOL MUTAGEN, V30, P139, DOI 10.1002/(SICI)1098-2280(1997)30:2<139::AID-EM6>3.0.CO

[4]

2-I

[5] Effects of chronic exposure to coal in wild rodents (Ctenomys torquatus) evaluated by multiple methods and tissues [J].

da Silva, J ;

de Freitas, TRO ;

Heuser, V ;

Marinho, JR ;

Bittencourt, F ;

Cerski, CTS ;

Kliemann, LM ;

Erdtmann, B .

MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS, 2000, 470 (01) :39-51

[6] An alkaline single-cell gel electrophoresis (comet) assay for environmental biomonitoring with native rodents [J].

da Silva, J ;

de Freitas, TRO ;

Marinho, JR ;

Speit, G ;

Erdtmann, B .

GENETICS AND MOLECULAR BIOLOGY, 2000, 23 (01) :241-245

[7]

DASILVA J, 2007, J BRAZILIAN SOC ECOT, V2, P45

[8] Toxicological assessment of ambient and traffic-related particulate matter:: A review of recent studies [J].

de Kok, Theo M. C. M. ;

Driece, Hermen A. L. ;

Hogervorst, Janneke G. F. ;

Briede, Jacob J. .

MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH, 2006, 613 (2-3) :103-122

[9] Mutagenic activity of airborne particulate matter as an indicative measure of atmospheric pollution [J].

Ducatti, A ;

Vargas, VMF .

MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS, 2003, 540 (01) :67-77

[10] WOOD-BURNING AS A SOURCE OF ATMOSPHERIC POLYCYCLIC AROMATIC-HYDROCARBONS [J].

FREEMAN, DJ ;

CATTELL, FCR .

ENVIRONMENTAL SCIENCE & TECHNOLOGY, 1990, 24 (10) :1581-1585

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