Lycochinines A-C, novel C27N3 alkaloids from Lycopodium chinense

被引：12

作者：

Hirasawa, Yusuke ^{[1
]}

Tanaka, Tomoyuki ^{[1
]}

Koyama, Koichiro ^{[1
]}

Morita, Hiroshi ^{[1
]}

机构：

[1] Hoshi Univ, Fac Pharmaceut Sci, Shinagawa Ku, Tokyo 1428501, Japan

来源：

TETRAHEDRON LETTERS | 2009年 / 50卷 / 34期

关键词：

1ST TOTAL-SYNTHESIS; INHIBITING ACETYLCHOLINESTERASE; MAGELLANINE; HAMILTONII;

D O I：

10.1016/j.tetlet.2009.05.072

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Three novel C27N3-type Lycopodium alkaloids, lycochinines A-C (1-3) consisting of an octahydroquinoline or a decahydroquinoline, a quinolizidine, and a piperidine, were isolated from the club moss Lycopodium chinense. The relative stereochemistry of 1-3 was determined by a combination of NOESY correlations and chemical transformations. (c) 2009 Elsevier Ltd. All rights reserved.

引用

页码：4816 / 4819

页数：4

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