Cobalt Catalyzed C-H and N-H Bond Annulation of Sulfonamide with Terminal and Internal Alkynes

被引：136

作者：

Kalsi, Deepti ^{[1
]}

Sundararaju, Basker ^{[1
]}

机构：

[1] Indian Inst Technol Kanpur, Dept Chem, Fine Chem Lab, Kanpur, Uttar Pradesh, India

来源：

ORGANIC LETTERS | 2015年 / 17卷 / 24期

关键词：

UNACTIVATED C(SP(3))-H BONDS; LATE-STAGE DIVERSIFICATION; ALIPHATIC AMIDES; DIRECT ARYLATION; ACTIVATION; FUNCTIONALIZATIONS; ACCESS; ALKENYLATIONS; ALKYLATIONS; OLEFINATION;

D O I：

10.1021/acs.orglett.5b03142

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Chelate assisted cobalt catalyzed C-H and N-H annulation of aryl sulfonamide with terminal and internal ales is reported. Very high regioselectivity and excellent functional group tolerance were achieved using Oxygen as a co-oxidant. The reaction is scalable under mild conditions.

引用

页码：6118 / 6121

页数：4

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