Cobalt Catalyzed C-H and N-H Bond Annulation of Sulfonamide with Terminal and Internal Alkynes

被引:136
作者
Kalsi, Deepti [1 ]
Sundararaju, Basker [1 ]
机构
[1] Indian Inst Technol Kanpur, Dept Chem, Fine Chem Lab, Kanpur, Uttar Pradesh, India
关键词
UNACTIVATED C(SP(3))-H BONDS; LATE-STAGE DIVERSIFICATION; ALIPHATIC AMIDES; DIRECT ARYLATION; ACTIVATION; FUNCTIONALIZATIONS; ACCESS; ALKENYLATIONS; ALKYLATIONS; OLEFINATION;
D O I
10.1021/acs.orglett.5b03142
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Chelate assisted cobalt catalyzed C-H and N-H annulation of aryl sulfonamide with terminal and internal ales is reported. Very high regioselectivity and excellent functional group tolerance were achieved using Oxygen as a co-oxidant. The reaction is scalable under mild conditions.
引用
收藏
页码:6118 / 6121
页数:4
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