Cutaneous allodynia is more frequent in chronic migraine, and its presence and severity seems to be more associated with the duration of the disease

被引:22
作者
Benatto, Mariana Tedeschi [1 ]
Florencio, Lidiane Lima [1 ]
Carvalho, Gabriela Ferreira [1 ]
Dach, Fabiola [2 ]
Bigal, Marcelo Eduardo [3 ]
Chaves, Thas Cristina [2 ]
Bevilaqua-Grossi, Debora [1 ,4 ]
机构
[1] Univ Sao Paulo, Fac Med Ribeirao Preto, Dept Biomecan Med & Reabilitacao Aparelho Locomot, Programa Posgrad Reabilitacao Desempenho Funct, Ribeirao Preto, SP, Brazil
[2] Univ Sao Paulo, Fac Med Ribeirao Preto, Dept Neurociencias Ciencias Comportamento, Ribeirao Preto, SP, Brazil
[3] Desenvolvimento Global Teva Pharmaceut Ind Ltd, Filadelfia, PA USA
[4] Univ Sao Paulo, Fac Med Ribeirao Preto, Lab Analises Postura & Movimento Humano LAPOMH, Ribeirao Preto, SP, Brazil
基金
巴西圣保罗研究基金会;
关键词
hyperalgesia; migraine disorders; TRANSFORMED MIGRAINE; PAIN; EPIDEMIOLOGY;
D O I
10.1590/0004-282X20170015
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Objective: To evaluate cutaneous allodynia among patients with chronic and episodic migraine in a tertiary headache clinic. Methods: 80 subjects with episodic migraine and 80 with chronic migraine were assessed in a tertiary hospital. The 12-item Allodynia Symptom Checklist/Brazil questionnaire was applied to classify subjects according to the presence and severity of cutaneous allodynia. Results: Cutaneous allodynia was identified in 81.3% of the episodic migraine group and 92.5% of the chronic migraine group (p = 0.03). No increased association could be attributed to chronic migraine when adjusted by years with disease (PR = 1.12; 95%CI = 0.99 to 1.27; p = 0.06). The groups also did not differ in the severity of allodynia, and severe presentation was the most frequent. Discussion: Both groups seemed to be similarly affected in the cephalic and extracephalic regions, with the same severity. Conclusion: Cutaneous allodynia is more frequent in chronic migraine, and its presence and severity seems to be more associated with the duration of the disease.
引用
收藏
页码:153 / 159
页数:7
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