Cutaneous allodynia is more frequent in chronic migraine, and its presence and severity seems to be more associated with the duration of the disease

被引:18
作者
Benatto, Mariana Tedeschi [1 ]
Florencio, Lidiane Lima [1 ]
Carvalho, Gabriela Ferreira [1 ]
Dach, Fabiola [2 ]
Bigal, Marcelo Eduardo [3 ]
Chaves, Thas Cristina [2 ]
Bevilaqua-Grossi, Debora [1 ,4 ]
机构
[1] Univ Sao Paulo, Fac Med Ribeirao Preto, Dept Biomecan Med & Reabilitacao Aparelho Locomot, Programa Posgrad Reabilitacao Desempenho Funct, Ribeirao Preto, SP, Brazil
[2] Univ Sao Paulo, Fac Med Ribeirao Preto, Dept Neurociencias Ciencias Comportamento, Ribeirao Preto, SP, Brazil
[3] Desenvolvimento Global Teva Pharmaceut Ind Ltd, Filadelfia, PA USA
[4] Univ Sao Paulo, Fac Med Ribeirao Preto, Lab Analises Postura & Movimento Humano LAPOMH, Ribeirao Preto, SP, Brazil
基金
巴西圣保罗研究基金会;
关键词
hyperalgesia; migraine disorders; TRANSFORMED MIGRAINE; PAIN; EPIDEMIOLOGY;
D O I
10.1590/0004-282X20170015
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Objective: To evaluate cutaneous allodynia among patients with chronic and episodic migraine in a tertiary headache clinic. Methods: 80 subjects with episodic migraine and 80 with chronic migraine were assessed in a tertiary hospital. The 12-item Allodynia Symptom Checklist/Brazil questionnaire was applied to classify subjects according to the presence and severity of cutaneous allodynia. Results: Cutaneous allodynia was identified in 81.3% of the episodic migraine group and 92.5% of the chronic migraine group (p = 0.03). No increased association could be attributed to chronic migraine when adjusted by years with disease (PR = 1.12; 95%CI = 0.99 to 1.27; p = 0.06). The groups also did not differ in the severity of allodynia, and severe presentation was the most frequent. Discussion: Both groups seemed to be similarly affected in the cephalic and extracephalic regions, with the same severity. Conclusion: Cutaneous allodynia is more frequent in chronic migraine, and its presence and severity seems to be more associated with the duration of the disease.
引用
收藏
页码:153 / 159
页数:7
相关论文
共 23 条
  • [1] Allodynia and migraine
    Aguggia, Marco
    [J]. NEUROLOGICAL SCIENCES, 2012, 33 : S9 - S11
  • [2] Improved identification of allodynic migraine patients using a questionnaire
    Ashkenazi, A.
    Silberstein, S.
    Jakubowski, M.
    Burstein, R.
    [J]. CEPHALALGIA, 2007, 27 (04) : 325 - 329
  • [3] Prevalence and characteristics of allodynia in headache sufferers - A population study
    Bigal, M. E.
    Ashina, S.
    Burstein, R.
    Reed, M. L.
    Buse, D.
    Serrano, D.
    Lipton, R. B.
    [J]. NEUROLOGY, 2008, 70 (17) : 1525 - 1533
  • [4] Burstein R, 2000, ANN NEUROL, V47, P614, DOI 10.1002/1531-8249(200005)47:5<614::AID-ANA9>3.0.CO
  • [5] 2-N
  • [6] Defeating migraine pain with triptans: A race against the development of cutaneous allodynia
    Burstein, R
    Collins, B
    Jakubowski, M
    [J]. ANNALS OF NEUROLOGY, 2004, 55 (01) : 19 - 26
  • [7] Thalamic Sensitization Transforms Localized Pain into Widespread Allodynia
    Burstein, Rami
    Jakubowski, Moshe
    Garcia-Nicas, Esther
    Kainz, Vanessa
    Bajwa, Zahid
    Hargreaves, Richard
    Becerra, Lino
    Borsook, David
    [J]. ANNALS OF NEUROLOGY, 2010, 68 (01) : 81 - 91
  • [8] Chronic migraine: definition, epidemiology, risk factors and treatment
    Carod-Artal, Francisco J.
    Irimia, Pablo
    Ezpeleta, David
    [J]. REVISTA DE NEUROLOGIA, 2012, 54 (10) : 629 - 637
  • [9] Cutaneous allodynia in transformed migraine patients
    Cooke, Lara
    Eliasziw, Michael
    Becker, Werner J.
    [J]. HEADACHE, 2007, 47 (04): : 531 - 539
  • [10] 12 item Allodynia Symptom Checklist/Brasil: cross-cultural adaptation, internal consistency and reproducibility
    Florencio, Lidiane Lima
    Chaves, Thais Cristina
    Branisso, Livia B.
    Goncalves, Maria Claudia
    Dach, Fabiola
    Speciali, Jose Geraldo
    Bigal, Marcelo Eduardo
    Bevilaqua-Grossi, Debora
    [J]. ARQUIVOS DE NEURO-PSIQUIATRIA, 2012, 70 (11) : 852 - 856