Polycaprolactone/Gelatin Nanofibrous Scaffolds for Tissue Engineering

被引：17

作者：

Farzamfar, Saeed ^{[1
]}

Aleahmad, Mehdi ^{[2
]}

Kouzehkonan, Gholamreza Savari ^{[3
]}

Salehi, Majid ^{[4
,5
,6
]}

Nazeri, Niloofar ^{[3
]}

机构：

[1] Univ Tehran Med Sci, Sch Adv Technol Med, Dept Tissue Engn & Cell Therapy, Tehran, Iran

[2] Univ Tehran Med Sci, Fac Publ Hlth, Dept Immunol, Tehran, Iran

[3] Univ Tehran Med Sci, Sch Adv Technol Med, Dept Med Nanotechnol, Tehran, Iran

[4] Shahroud Univ Med Sci, Sch Med, Dept Tissue Engn, Shahroud, Iran

[5] Shahroud Univ Med Sci, Tissue Engn & Stem Cells Res Ctr, Shahroud, Iran

[6] Shahroud Univ Med Sci, Sexual Hlth & Fertil Res Ctr, Shahroud, Iran

来源：

BIOINTERFACE RESEARCH IN APPLIED CHEMISTRY | 2021年 / 11卷 / 04期

关键词：

polycaprolactone; gelatin; nanofibers; tissue engineering; DRUG-DELIVERY SYSTEM; IN-VITRO; SURFACE FUNCTIONALIZATION; EXTRACELLULAR-MATRIX; GELATIN MICROSPHERES; COMPOSITE SCAFFOLD; CHITOSAN; FABRICATION; BLEND; DIFFERENTIATION;

D O I：

10.33263/BRIAC114.1110411115

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

The combined use of polycaprolactone and gelatin has obviated many drawbacks associated with applying them alone. Polycaprolactone provides mechanical strength and buys sufficient time for tissue regeneration without degradation. Simultaneously, gelatin regulates the surface wettability of the composite scaffold. It makes the structure more cytocompatible by its cell recognition sites. Furthermore, these low polymers' cost, biocompatibility, and tuning of degradation time have added to their therapeutic appeal. In the current study, we have reviewed the application of polycaprolactone/gelatin scaffolds in tissue engineering and drug delivery fields, hoping to translate these scaffolds into medicine. (C) 2020 by the authors.

引用

页码：11104 / 11115

页数：12

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