The tobacco mosaic virus resistance gene, N

被引：69

作者：

Marathe, R ^{[1
]}

Anandalakshmi, R ^{[1
]}

Liu, YL ^{[1
]}

Dinesh-Kumar, SP ^{[1
]}

机构：

[1] Yale Univ, Dept Mol Cellular & Dev Biol, New Haven, CT 06520 USA

来源：

MOLECULAR PLANT PATHOLOGY | 2002年 / 3卷 / 03期

关键词：

D O I：

10.1046/j.1364-3703.2002.00110.x

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

In this mini review we discuss recent advances in the understanding of the N gene-mediated resistance to tobacco mosaic virus (TMV). The tobacco N gene belongs to toll-interleukin-1 receptor homology/nucleotide binding/leucine rich repeat (TIR-NB-LRR) class of resistance genes. it encodes two transcripts, N-S and N-L, by alternative splicing, both of which are required to confer resistance to TMV. The structure-function analysis of the N gene indicates that the TIR, NB and LRR domains are indispensable for its function. The N gene response is elicited by the C-terminal helicase domain of the 126 kDa TMV replicase protein. Tobacco N gene can also confer resistance to TMV in heterologous plants like tomato and Nicotiana benthamiana. Recent studies on N-mediated signalling suggest that EDS1, Rar1 and NPR1 genes play an important role in TMV resistance. Finally, we discuss current status of the N-mediated signal transduction and speculate directions for future work to understand N-TMV interaction.

引用

页码：167 / 172

页数：6

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