Live immunization against East Coast fever - current status

被引：104

作者：

Di Giulio, Giuseppe ^{[2
]}

Lynen, Godelieve ^{[2
]}

Morzaria, Subhash ^{[3
]}

Oura, Chris ^{[4
]}

Bishop, Richard ^{[1
]}

机构：

[1] Int Livestock Res Inst, Nairobi, Kenya

[2] VetAgro Tanzania Ltd, Arusha, Tanzania

[3] Reg Off Asia & Pacific, FAO United Nations, Bangkok, Thailand

[4] AFRC, Inst Anim Hlth, Pirbright Lab, Woking GU24 0NF, Surrey, England

来源：

TRENDS IN PARASITOLOGY | 2009年 / 25卷 / 02期

基金：

英国惠康基金;

关键词：

THEILERIA-PARVA STOCKS; MOLECULAR EPIDEMIOLOGY; VACCINE; CATTLE; POPULATION; PERSISTENCE; DIVERSITY; IMMUNITY; DISEASES;

D O I：

10.1016/j.pt.2008.11.007

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

The infection-and-treatment method (ITM) for immunization of cattle against East Coast fever has historically been used only on a limited scale because of logistical and policy constraints. Recent large-scale deployment among pastoralists in Tanzania has stimulated demand. Concurrently, a suite of molecular tools, developed from the Theileria parva genome, has enabled improved quality control of the immunizing stabilate and post-immunization monitoring of the efficacy and biological impact of ITM in the field. This article outlines the current status of ITM immunization in the field, with associated developments in the molecular epidemiology of T. parva.

引用

页码：85 / 92

页数：8

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