Componential Profile and Amylase Inhibiting Activity of Phenolic Compounds from Calendula officinalis L. Leaves

被引：39

作者：

Olennikov, Daniil N. ^{[1
]}

Kashchenko, Nina I. ^{[1
]}

机构：

[1] Russian Acad Sci, Lab Med & Biol Res, Inst Gen & Expt Biol, Siberian Div, Ulan Ude 670047, Russia

来源：

SCIENTIFIC WORLD JOURNAL | 2014年

关键词：

GLYCOSIDES; CONSTITUENTS; ANTIOXIDANT; MARIGOLD; POLYSACCHARIDES;

D O I：

10.1155/2014/654193

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

An ethanolic extract and its ethyl acetate-soluble fraction from leaves of Calendula officinalis L. (Asteraceae) were found to show an inhibitory effect on amylase. From the crude extract fractions, one new phenolic acid glucoside, 6'-O-vanilloyl-beta-D-glucopyranose, was isolated, together with twenty-four known compounds including five phenolic acid glucosides, five phenylpropanoids, five coumarins, and nine flavonoids. Their structures were elucidated based on chemical and spectral data. The main components, isoquercitrin, isorhamnetin-3-O-beta-D-glucopyranoside, 3,5-di-O-caffeoylquinic acid, and quercetin-3-O-(6 ''-acetyl)-beta-D-glucopyranoside, exhibited potent inhibitory effects on amylase.

引用

页数：9

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