Death following ingestion of methylone

被引:42
作者
Barrios, L. [1 ]
Grison-Hernando, H. [2 ]
Boels, D. [3 ]
Bouquie, R. [2 ]
Monteil-Ganiere, C. [2 ]
Clement, R. [1 ]
机构
[1] CHU Nantes, Med Legale, 1 Pl Alexis Ricordeau, F-44093 Nantes 1, France
[2] CHU Nantes, Lab Pharmacol Toxicol, 9 Quai Moncousu, F-44093 Nantes 1, France
[3] CHU Angers, Ctr Antipoison, 4 Rue Larrey, F-49000 Angers, France
关键词
Methylone; Cathinones; Anoxia; Respiratory inhibition; Death; BATH SALTS; DRUG; ABUSE;
D O I
10.1007/s00414-015-1212-4
中图分类号
DF [法律]; D9 [法律]; R [医药、卫生];
学科分类号
0301 ; 10 ;
摘要
Methylone is a synthetic derivative of cathinone. It is sold principally on the Internet in powder form under the name A << bath saltsA >>. Deaths following consumption are very rare. This report details the first case of a death in France (a 21-year-old man), following ingestion of methylone during an evening with friends. Anoxia was observed at the time of autopsy. Toxicological analyses highlighted a consumption of methylone and cannabis. However, biological analyses showed an absence of ethanol, cocaine, amphetamines, and opiate derivatives. Likewise, no medications were found. High concentrations of methylone were found in the peripheral blood (3.13 mg/L) and in the central blood (6.64 mg/L). Its presence in the gastric contents provides evidence that the substance was taken orally. The dosage of delta 9-tetrahydrocannabinol (THC) suggests a recent cannabis consumption (THC 12.9 mu g/L, THC-COOH 29.3 mu g/L, 11-OH-THC 4.9 mu g/L). This case illustrates that the consumption of methylone, which has a reputation of being less A << powerfulA >> than ecstasy, is not without its dangers.
引用
收藏
页码:381 / 385
页数:5
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