Human and primate-specific microRNAs in cancer: Evolution, and significance in comparison with more distantly-related research models

被引：20

作者：

Koufaris, Costas ^{[1
]}

机构：

[1] Cyprus Inst Neurol & Genet, Dept Cytogenet & Genom, Nicosia, Cyprus

来源：

BIOESSAYS | 2016年 / 38卷 / 03期

基金：

欧盟地平线“2020”;

关键词：

cancer; evolution; human; lineage; microRNA; mouse; species; specific; BREAST-CANCER; HEPATOCELLULAR-CARCINOMA; HUMAN-CELLS; GENES; EXPRESSION; BRAIN; DIFFERENTIATION; IDENTIFICATION; TRANSCRIPTION; CLUSTER;

D O I：

10.1002/bies.201500135

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The largest proportion of microRNAs in humans (ca. 40-50%) originated in the phylogenetic grouping defined as primates. The dynamic evolution of this family of noncoding RNA is further demonstrated by the presence of microRNA unique to the human species. Investigations into the role of microRNA in cancer have until recently mainly focused on the more ancient members of this RNA family that are widely conserved in the animal kingdom. As I describe in this review the evolutionary young lineage and species-specific microRNA could be important contributors to cancers, especially in particular organs in primates compared to more distantly-related research models. Elucidating the biological significance of primate and human-specific microRNA in cancer could have important implications for cancer research and the use of nonprimate animal models.

引用

页码：286 / 294

页数：9

共 68 条

[41] The birth and death of microRNA genes in Drosophila [J].

Lu, Jian ;

Shen, Yang ;

Wu, Qingfa ;

Kumar, Supriya ;

He, Bin ;

Shi, Suhua ;

Carthew, Richard W. ;

Wang, San Ming ;

Wu, Chung-I .

NATURE GENETICS, 2008, 40 (03) :351-355

[42] A microenvironment-mediated c-Myc/miR-548m/HDAC6 amplification loop in non-Hodgkin B cell lymphomas [J].

Lwin, Tint ;

Zhao, Xiaohong ;

Cheng, Fengdong ;

Zhang, Xinwei ;

Huang, Andy ;

Shah, Bijal ;

Zhang, Yizhuo ;

Moscinski, Lynn C. ;

Choi, Yong Sung ;

Kozikowski, Alan P. ;

Bradner, James E. ;

Dalton, William S. ;

Sotomayor, Eduardo ;

Tao, Jianguo .

JOURNAL OF CLINICAL INVESTIGATION, 2013, 123 (11) :4612-4626

[43] Birth and expression evolution of mammalian microRNA genes [J].

Meunier, Julien ;

Lemoine, Frederic ;

Soumillon, Magali ;

Liechti, Angelica ;

Weier, Manuela ;

Guschanski, Katerina ;

Hu, Haiyang ;

Khaitovich, Philipp ;

Kaessmann, Henrik .

GENOME RESEARCH, 2013, 23 (01) :34-45

[44] Species-specific microRNA regulation influences phenotypic variability Perspectives on species-specific microRNA regulation [J].

Mor, Eyal ;

Shomron, Noam .

BIOESSAYS, 2013, 35 (10) :881-888

[45] Single-Nucleotide Polymorphisms Inside MicroRNA Target Sites Influence Tumor Susceptibility [J].

Nicoloso, Milena S. ;

Sun, Hao ;

Spizzo, Riccardo ;

Kim, Hyunsoo ;

Wickramasinghe, Priyankara ;

Shimizu, Masayoshi ;

Wojcik, Sylwia E. ;

Ferdin, Jana ;

Kunej, Tanja ;

Xiao, Lianchun ;

Manoukian, Siranoush ;

Secreto, Giorgio ;

Ravagnani, Fernando ;

Wang, Xuemei ;

Radice, Paolo ;

Croce, Carlo M. ;

Davuluri, Ramana V. ;

Calin, George A. .

CANCER RESEARCH, 2010, 70 (07) :2789-2798

[46] The cooked meat-derived mammary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) elicits estrogenic-like microRNA responses in breast cancer cells [J].

Papaioannou, M. D. ;

Koufaris, C. ;

Gooderham, N. J. .

TOXICOLOGY LETTERS, 2014, 229 (01) :9-16

[47] MicroRNA 4423 is a primate-specific regulator of airway epithelial cell differentiation and lung carcinogenesis [J].

Perdomo, Catalina ;

Campbell, Joshua D. ;

Gerrein, Joseph ;

Tellez, Carmen S. ;

Garrison, Carly B. ;

Walser, Tonya C. ;

Drizik, Eduard ;

Si, Huiqing ;

Gower, Adam C. ;

Vick, Jessica ;

Anderlind, Christina ;

Jackson, George R. ;

Mankus, Courtney ;

Schembri, Frank ;

O'Hara, Carl ;

Gomperts, Brigitte N. ;

Dubinett, Steven M. ;

Hayden, Patrick ;

Belinsky, Steven A. ;

Lenburg, Marc E. ;

Spira, Avrum .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2013, 110 (47) :18946-18951

[48] A Family of Human MicroRNA Genes from Miniature Inverted-Repeat Transposable Elements [J].

Piriyapongsa, Jittima ;

Jordan, I. King .

PLOS ONE, 2007, 2 (02)

[49] A Burst of miRNA Innovation in the Early Evolution of Butterflies and Moths [J].

Quah, Shan ;

Hui, Jerome H. L. ;

Holland, Peter W. H. .

MOLECULAR BIOLOGY AND EVOLUTION, 2015, 32 (05) :1161-1174

[50] Decreased miRNA-637 is an unfavorable prognosis marker and promotes glioma cell growth, migration and invasion via direct targeting Akt1 [J].

Que, T. ;

Song, Y. ;

Liu, Z. ;

Zheng, S. ;

Long, H. ;

Li, Z. ;

Liu, Y. ;

Wang, G. ;

Liu, Y. ;

Zhou, J. ;

Zhang, X. ;

Fang, W. ;

Qi, S. .

ONCOGENE, 2015, 34 (38) :4952-4963

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