The solder materials used to make the solder joints for this study are: eutectic Sn-3Ag-0.5Cu solder, Sn-3Ag-0.5Cu-1Bi solder, Sn-3Ag-0.5Cu-3Bi quaternary solder. In order to study the microstructures evolution and the growth kinetic of IMC, aging the solder joints isothermally in resistance oven at 150 +/- 5 V with different periods of 0, 50, 100, 250, 500, 1000hours. The result show that: the morphology of IMC become from scallop-like to planar in aging process, the mean thickness of IMC layer solder joints is found to increase linearly with the square root of aging time, namely the growth of IMC controlled by atom diffusion, the IMC growth rate decreased as Bi content increased, for the solders discussed above the comparative IMC growth rate sequence from fast to slow is Sn-3Ag-0.5Cu > Sn-3Ag-0.5Cu-1Bi > Sn-3Ag-MCu-Mi.