MHC class II B genes in the channel catfish (Ictalurus punctatus)

被引：47
作者：
Godwin, UB
Antao, A
Wilson, MR
Chinchar, VG
Miller, NW
Clem, LW
McConnell, TJ
机构：
[1] E CAROLINA UNIV,DEPT BIOL,GREENVILLE,NC 27858
[2] UNIV MISSISSIPPI,MED CTR,DEPT MICROBIOL,JACKSON,MS 39216
来源：
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY | 1997年 / 21卷 / 01期
关键词：
channel catfish; major histocompatibility complex; MHC class II B genes; MHC class II beta chains;
D O I：
10.1016/S0145-305X(97)00003-7
中图分类号：
S9 [水产、渔业];
学科分类号：
0908 ;
摘要：
Two different cDNA sequences for major histocompatibility complex (MHC) class II beta chains from the channel catfish (Ictalurus punctatus) have been identified. Homology between these sequences and those previously identified as MHC class II B genes in other teleosts suggests they represent alleles of the DAB locus. The inferred amino acid sequences show strong evidence for a functional polypeptide chain with a peptide binding region. Southern blot analysis reveals polymorphism in the MHC class II B gene(s) of the channel catfish and suggests the presence of two to four genes. (C) 1997 Elsevier Science Ltd.
引用
收藏
页码：13 / 23
页数：11
相关论文
共 43 条
12345