Inorganic-biomolecular hybrid nanomaterials as a genetic molecular code system

被引：102
作者：
Choy, JH [1 ]
Oh, JM
Park, M
Sohn, KM
Kim, JW
机构：
[1] Seoul Natl Univ, Sch Chem & Mol Engn, NNML, Seoul 151747, South Korea
[2] Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Lab Med, Seoul 135710, South Korea
来源：
ADVANCED MATERIALS | 2004年 / 16卷 / 14期
关键词：
D O I：
10.1002/adma.200400027
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A molecular-level coding method utilizing DNA base pairs as code units has been systemized. The system consists of four steps: encoding, encrypting, decrypting and decoding (see Figure), which are realized by tailor-made nanohybrids (DNA-layered double hydroxide (LDH) and polypyrrole-maghemite). The nanohybrids give solutions to the inherent problems which hamper DNA molecular code systems; stability in encrypting and rapidity in analysis.
引用
收藏
页码：1181 / +
页数：5
相关论文
共 18 条
[1]   Molecular systematics - Counting angels with DNA [J].
Blaxter, M .
NATURE, 2003, 421 (6919) :122-124
[2]  
Choy JH, 2000, ANGEW CHEM INT EDIT, V39, P4042
[3]   Intercalative nanohybrids of nucleoside monophosphates and DNA in layered metal hydroxide [J].
Choy, JH ;
Kwak, SY ;
Park, JS ;
Jeong, YJ ;
Portier, J .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1999, 121 (06) :1399-1400
[4]   Hiding messages in DNA microdots [J].
Clelland, CT ;
Risca, V ;
Bancroft, C .
NATURE, 1999, 399 (6736) :533-534
[5]   Long-term data storage in DNA [J].
Cox, JPL .
TRENDS IN BIOTECHNOLOGY, 2001, 19 (07) :247-250
[6]   Bar coding objects with DNA [J].
Cox, JPL .
ANALYST, 2001, 126 (05) :545-547
[7]  
Eckstein F., 1991, OLIGONUCLEOTIDES ANA
[8]   A new polypyrrole/maghemite hybrid as a lithium insertion electrode [J].
Kwon, CW ;
Poquet, A ;
Mornet, S ;
Campet, G ;
Portier, J ;
Choy, JH .
ELECTROCHEMISTRY COMMUNICATIONS, 2002, 4 (02) :197-200
[9]   PREPARATION OF AQUEOUS MAGNETIC LIQUIDS IN ALKALINE AND ACIDIC MEDIA [J].
MASSART, R .
IEEE TRANSACTIONS ON MAGNETICS, 1981, 17 (02) :1247-1248
[10]  
MASSART R, 1990, Patent No. 2662539
12