The IASLC/ITMIG Thymic Epithelial Tumors Staging Project: Proposal for an Evidence-Based Stage Classification System for the Forthcoming (8th) Edition of the TNM Classification of Malignant Tumors

被引:319
作者
Detterbeck, Frank C. [1 ]
Stratton, Kelly
Giroux, Dorothy
Asamura, Hisao [2 ]
Crowley, John
Falkson, Conrad [3 ]
Filosso, Pier Luigi [4 ]
Frazier, Aletta A. [15 ]
Giaccone, Giuseppe [5 ]
Huang, James [6 ]
Kim, Jhingook [7 ]
Kondo, Kazuya [8 ]
Lucchi, Marco [9 ]
Marino, Mirella [10 ]
Marom, Edith M. [11 ]
Nicholson, Andrew G. [12 ]
Okumura, Meinoshin [13 ]
Ruffini, Enrico [4 ]
Van Schil, Paul [14 ]
机构
[1] Yale Univ, New Haven, CT 06520 USA
[2] Natl Canc Ctr, Tokyo, Japan
[3] Queens Univ, Kingston, ON K7L 3N6, Canada
[4] Univ Turin, Turin, Italy
[5] Georgetown Univ, Washington, DC USA
[6] Mem Sloan Kettering Canc Ctr, New York, NY 10021 USA
[7] Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Seoul, South Korea
[8] Univ Tokushima, Tokushima 770, Japan
[9] Univ Pisa, Pisa, Italy
[10] Regina Elena Inst Canc Res, Rome, Italy
[11] Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USA
[12] Royal Brompton Hosp, London SW3 6LY, England
[13] Osaka Univ, Osaka, Japan
[14] Univ Antwerp Hosp, Antwerp, Belgium
[15] Univ Maryland, Baltimore, MD 21201 USA
关键词
Staging; Prognosis; Thymoma; Thymic carcinoma; Stage classification; THYMOMAS;
D O I
10.1097/JTO.0000000000000290
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
A universal and consistent stage classification system, which describes the anatomic extent of a cancer, provides a foundation for communication and collaboration. Thymic epithelial malignancies have seen little progress, in part because of the lack of an official system. The International Association for the Study of Lung Cancer and the International Thymic Malignancies Interest Group assembled a large retrospective database, a multispecialty international committee and carried out extensive analysis to develop proposals for the 8th edition of the stage classification manuals. This tumor, node, metastasis (TNM)-based system is applicable to all types of thymic epithelial malignancies. This article summarizes the proposed definitions of the T, N, and M components and describes how these are combined into stage groups. This represents a major step forward for thymic malignancies.
引用
收藏
页码:S65 / S72
页数:8
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