Free radical scavenging of Ganoderma lucidum polysaccharides and its effect on antioxidant enzymes and immunity activities in cervical carcinoma rats

被引：134
作者：
Chen XiaoPing [1 ]
Chen Yan [1 ]
Li ShuiBing
Chen YougGuo [2 ,3 ]
Lan JianYun
Liu LanPing
机构：
[1] YanCheng 1 People Hosp, Dept Obstet & Gynecol, Yancheng City 224000, Jiangsu, Peoples R China
[2] Soochow Univ, Affiliated Hosp 1, Dept Obstet & Gynecol, Suzhou 215006, Peoples R China
[3] YanCheng 1 People Hosp, Dept Pathol, Yancheng City 224000, Jiangsu, Peoples R China
来源：
CARBOHYDRATE POLYMERS | 2009年 / 77卷 / 02期
关键词：
Ganoderma lucidum polysaccharides; Rat; Antioxidant activity; Free radical; Immunity; CULTURE PROCESS; IN-VITRO; ACID; HYPERPRODUCTION; FERMENTATION; FRACTIONS; MUSHROOM; EXTRACTS; OXYGEN; CELLS;
D O I：
10.1016/j.carbpol.2009.01.009
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Ganoderma lucidum are used as traditional edible and medicinal materials in China. In this study, antioxidant activities of polysaccharides from G. lucidum in China were investigated. The influence of G. lucidum polysaccharides upon activities of serum antioxidant enzymes and immunity in rats with cervical cancer. The antioxidant activity was measured by DPPH-, O-, and OH- free radicals scavenging. Results showed that G. lucidum polysaccharides exhibited the higher DPPH-, O-, and OH- free radicals scavenging activities. The results still showed that G. lucidum polysaccharides could significantly enhance the antioxidant enzyme activities (SOD, CAT and GPx), and reduce levels of IL-1 beta, IL-6 and TNF-alpha in rats with cervical cancer. (C) 2009 Elsevier Ltd. All rights reserved.
引用
收藏
页码：389 / 393
页数：5
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