Lateral flow assays

被引:809
作者
Koczula, Katarzyna M. [1 ]
Gallotta, Andrea [1 ]
机构
[1] Xeptagen SpA, VEGA Sci Pk,Via Ind 9, Venice, Italy
来源
BIOSENSOR TECHNOLOGIES FOR DETECTION OF BIOMOLECULES | 2016年 / 60卷 / 01期
关键词
SENSITIVE DETECTION; IMMUNOCHROMATOGRAPHIC ASSAY; GOLD NANOPARTICLES; STRIP BIOSENSOR; BOVINE ANTIBODY; RAPID DETECTION; IMMUNOASSAY; PROTEIN; OLIGONUCLEOTIDE; VIRUS;
D O I
10.1042/EBC20150012
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Lateral flow assays (LFAs) are the technology behind low-cost, simple, rapid and portable detection devices popular in biomedicine, agriculture, food and environmental sciences. This review presents an overview of the principle of the method and the critical components of the assay, focusing on lateral flow immunoassays. This type of assay has recently attracted considerable interest because of its potential to provide instantaneous diagnosis directly to patients. The range and interpretation of results and parameters used for evaluation of the assay will also be discussed. The main advantages and disadvantages of LFAs will be summarized and relevant future improvements to testing devices and strategies will be proposed. Finally, the major recent advances and future diagnostic applications in the LFA field will be explored.
引用
收藏
页码:111 / 120
页数:10
相关论文
共 54 条
[1]   Increased sensitivity of lateral flow immunoassay for ochratoxin A through silver enhancement [J].
Anfossi, L. ;
Di Nardo, F. ;
Giovannoli, C. ;
Passini, C. ;
Baggiani, C. .
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2013, 405 (30) :9859-9867
[2]   Quantitative, single-step dual measurement of hemoglobin A1c and total hemoglobin in human whole blood using a gold sandwich immunochromatographic assay for personalized medicine [J].
Ang, Shu Hwang ;
Rambeli, Musalman ;
Thevarajah, T. Malathi ;
Alias, Yatimah Binti ;
Khor, Sook Mei .
BIOSENSORS & BIOELECTRONICS, 2016, 78 :187-193
[3]  
[Anonymous], 2008, Rapid Lateral Flow Test Strips
[4]   Development of Prototype Filovirus Recombinant Antigen Immunoassays [J].
Boisen, Matt L. ;
Oottamasathien, Darin ;
Jones, Abigail B. ;
Millett, Molly M. ;
Nelson, Diana S. ;
Bornholdt, Zachary A. ;
Fusco, Marnie L. ;
Abelson, Dafna M. ;
Oda, Shun-ichiro ;
Hartnett, Jessica N. ;
Rowland, Megan M. ;
Heinrich, Megan L. ;
Akdag, Marjan ;
Goba, Augustine ;
Momoh, Mambu ;
Fullah, Mohammed ;
Baimba, Francis ;
Gbakie, Michael ;
Safa, Sadiki ;
Fonnie, Richard ;
Kanneh, Lansana ;
Cross, Robert W. ;
Geisbert, Joan B. ;
Geisbert, Thomas W. ;
Kulakosky, Peter C. ;
Grant, Donald S. ;
Shaffer, Jeffery G. ;
Schieffelin, John S. ;
Wilson, Russell B. ;
Saphire, Erica Ollmann ;
Branco, Luis M. ;
Garry, Robert F. ;
Khan, S. Humarr ;
Pitts, Kelly R. .
JOURNAL OF INFECTIOUS DISEASES, 2015, 212 :S359-S367
[5]  
Butler SA, 2001, CLIN CHEM, V47, P2131
[6]   Automated Low-Cost Smartphone-Based Lateral Flow Saliva Test Reader for Drugs-of-Abuse Detection [J].
Carrio, Adrian ;
Sampedro, Carlos ;
Luis Sanchez-Lopez, Jose ;
Pimienta, Miguel ;
Campoy, Pascual .
SENSORS, 2015, 15 (11) :29569-29593
[7]   Computational Lateral Flow Biosensor for Proteins and Small Molecules: A New Class of Strip Logic Gates [J].
Chen, Junhua ;
Fang, Zhiyuan ;
Lie, Puchang ;
Zeng, Lingwen .
ANALYTICAL CHEMISTRY, 2012, 84 (15) :6321-6325
[8]   Detection of Shiga Toxins by Lateral Flow Assay [J].
Ching, Kathryn H. ;
He, Xiaohua ;
Stanker, Larry H. ;
Lin, Alice V. ;
McGarvey, Jeffery A. ;
Hnasko, Robert .
TOXINS, 2015, 7 (04) :1163-1173
[9]   Human pathogenic Cryptosporidium species bioanalytical detection method with single oocyst detection capability [J].
Connelly, John T. ;
Nugen, Sam R. ;
Borejsza-Wysocki, Wlodek ;
Durst, Richard A. ;
Montagna, Richard A. ;
Baeumner, Antje J. .
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2008, 391 (02) :487-495
[10]  
De Giovanni N, 2013, CURR MED CHEM, V20, P545