Prevalence of anelloviruses (TTV, TTMDV, and TTMV) in healthy blood donors and in patients infected with HBV or HCV in Qatar

被引:43
作者
Al-Qahtani, Ahmed A. [1 ,2 ,3 ]
Alabsi, Enas S. [4 ,5 ]
AbuOdeh, Raed [6 ]
Thalib, Lukman [4 ]
Nasrallah, Gheyath K. [4 ,5 ]
机构
[1] King Faisal Specialist Hosp & Res Ctr, Res Ctr, Dept Infect & Immunity, Riyadh, Saudi Arabia
[2] Alfaisal Univ, Sch Med, Dept Microbiol & Immunol, Riyadh, Saudi Arabia
[3] King Saud Univ, Liver Dis Res Ctr, Riyadh, Saudi Arabia
[4] Qatar Univ, Coll Arts Sci, Dept Hlth Sci, POB 2713, Doha, Qatar
[5] Qatar Univ, Biomed Res Ctr, Doha, Qatar
[6] Univ Sharjah, Dept Med Lab Sci, Sharjah, U Arab Emirates
来源
VIROLOGY JOURNAL | 2016年 / 13卷
关键词
Anelloviruses; HBV; HCV; PCR; TORQUE TENO VIRUS; MINI-VIRUS; DNA VIRUS; IDENTIFICATION; HEPATITIS; CHILDREN;
D O I
10.1186/s12985-016-0664-6
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Background: Anelloviruses (TTV, TTMV, and TTMDV) have been associated with non A-G hepatitis. The goal of the current study was to estimate the prevalence of these anelloviruses in Qatar. Methods: A total of 607 blood samples (500 healthy donors, and 53 HBV-and 54 HCV-positive patients) representing different nationalities were tested for the presence of TTV, TTMV, and TTMDV DNA by nested PCR. Results: Prevalence rates for the three viruses were high in all studied groups, and exceeding 95% in the HBV group (for TTV and TTMDV). Infection with more than one type of viruses was common and significant in most of the positive patients (p < 0.05) and ranging from 55.4% for TTV/TTMV and TTMV/TTMDV co-infections in the healthy group, to 96.3% for TTV/TTMV co-infections in the HBV group. Further, and as with most previous studies, no significant association was found between anelloviruses infections and age, nationality, or gender (p > 0.05) albeit the detection of higher infection rates among females and Qatari subjects. Conclusion: This was the first published study to look at prevalence of Anellowviruses in the Middle East. High prevalence rates of the three viruses in all studied groups was noted. Further studies are needed to explore and compare the different genotypes of these viruses in the region.
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页码:1 / 6
页数:6
相关论文
共 31 条
  • [1] Detection and Genotyping of Torque Teno Virus (TTV) in Healthy Blood Donors and Patients Infected With HBV or HCV in Qatar
    AbuOdeh, Raed
    Al-Mawlawi, Naema
    Al-Qahtani, Ahmed A.
    Bohol, Marie Fe F.
    Al-Ahdal, Mohammed N.
    Hasan, Haydar A.
    AbuOdeh, Lamees
    Nasrallah, Gheyath K.
    [J]. JOURNAL OF MEDICAL VIROLOGY, 2015, 87 (07) : 1184 - 1191
  • [2] Small anellovirus in hepatitis C patients and healthy controls
    Andreoli, Elisabetta
    Maggi, Fabrizio
    Pistello, Mauro
    Meschi, Silvia
    Vatteroni, Marialinda
    Nelli, Luca Ceccherini
    Bendinelli, Mauro
    [J]. EMERGING INFECTIOUS DISEASES, 2006, 12 (07) : 1175 - 1176
  • [3] Identification of a third member of the Anellovirus genus ("small anellovirus") in French blood donors
    Biagini, P
    de Micco, P
    de Lamballerie, X
    [J]. ARCHIVES OF VIROLOGY, 2006, 151 (02) : 405 - 408
  • [4] Biagini P, 2009, CURR TOP MICROBIOL, V331, P21
  • [5] TT virus and TT virus-like mini-virus infection in French blood donors
    Biagini, P
    Gallian, P
    de Micco, P
    de Lamballerie, X
    [J]. TRANSFUSION, 2000, 40 (12) : 1542 - 1542
  • [6] Detection and follow-up of torque teno midi virus ("small anelloviruses") in nasopharyngeal aspirates and three other human body fluids in children
    Burian, Zsofia
    Szabo, Hajnalka
    Szekely, Gyoengyi
    Gyurkovits, Kalman
    Pankovics, Peter
    Farkas, Tibor
    Reuter, Gabor
    [J]. ARCHIVES OF VIROLOGY, 2011, 156 (09) : 1537 - 1541
  • [7] Torque Teno Mini Virus Infection in Chronic Cervicitis and Cervical Tumors in Isfahan, Iran
    Changani, Leila
    Bouzari, Majid
    Talebi, Ardeshir
    [J]. INTERVIROLOGY, 2013, 56 (04) : 265 - 270
  • [8] Small anellovirus infections in Korean children
    Chung, Ju-Young
    Han, Tae Hee
    Koo, Ja Wook
    Kim, Sang Woo
    Seo, Jeong Kee
    Hwang, Eung Soo
    [J]. EMERGING INFECTIOUS DISEASES, 2007, 13 (05) : 791 - 793
  • [9] Chung JY, 2004, KOREAN J LAB MED, V28, P250
  • [10] Torque Teno Midi Virus/Small Anellovirus in Sera of Healthy, HIV/HCV and HIV Infected Individuals in Lorestan Province, Iran
    Fatholahi, Maryam
    Bouzari, Majid
    [J]. JUNDISHAPUR JOURNAL OF MICROBIOLOGY, 2015, 8 (11)