Enantioselective hydrogenation of acyclic aromatic N-aryl imines catalyzed by an iridium complex of (S,S)-1,2-bis(tert-butylmethylphosphino)ethane

被引：93
作者：
Imamoto, Tsuneo [1 ]
Iwadate, Noriyuki [1 ]
Yoshida, Kazuhiro [1 ]
机构：
[1] Chiba Univ, Fac Sci, Dept Chem, Inage Ku, Chiba 2638522, Japan
来源：
ORGANIC LETTERS | 2006年 / 8卷 / 11期
关键词：
D O I：
10.1021/ol060546b
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An iridium(I) complex of (S,S)-1,2-bis(tert-butylmethylphosphino)ethane with tetrakis(3,5-bis(trifluoromethyl)phenyl) borate as the counterion catalyzes the hydrogenation of acyclic aromatic N-aryl imines under 1 atm of hydrogen pressure at room temperature to give the corresponding optically active secondary amines with up to 99% ee.
引用
收藏
页码：2289 / 2292
页数：4
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