Hereditary non-polyposis colorectal cancer:: current risks of colorectal cancer largely overestimated

被引:50
作者
Carayol, J
Khlat, M
Maccario, J
Bonaïti-Pellié, C
机构
[1] CHU Kremlin Bicetre, INSERM, U535, Unite Rech Genet Epidemiol & Struct Populat Human, F-94276 Le Kremlin Bicetre, France
[2] Inst Gustave Roussy, INSERM, U521, Unite Rech Epidemiol Canc, F-94805 Villejuif, France
[3] INSERM, U472, Unite Rech Epidemiol, Paris, France
关键词
D O I
10.1136/jmg.39.5.335
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
引用
收藏
页码:335 / 339
页数:5
相关论文
共 29 条
[1]   Incidence of hereditary nonpolyposis colorectal cancer and the feasibility of molecular screening for the disease [J].
Aaltonen, LA ;
Salovaara, R ;
Kristo, P ;
Canzian, F ;
Hemminki, A ;
Peltomäki, P ;
Chadwick, RB ;
Kääriäinen, H ;
Eskelinen, M ;
Järvinen, H ;
Mecklin, JP ;
de la Chapelle, A ;
Percesepe, A ;
Ahtola, H ;
Härkönen, N ;
Julkunen, R ;
Kangas, E ;
Ojala, S ;
Tulikoura, J ;
ValKamo, E .
NEW ENGLAND JOURNAL OF MEDICINE, 1998, 338 (21) :1481-1487
[2]  
Aarnio M, 1999, INT J CANCER, V81, P214, DOI 10.1002/(SICI)1097-0215(19990412)81:2<214::AID-IJC8>3.3.CO
[3]  
2-C
[4]   Life-time risk of different cancers in hereditary non-polyposis colorectal cancer (HNPCC) syndrome [J].
Aarnio, M ;
Mecklin, JP ;
Aaltonen, LA ;
NystromLahti, M ;
Jarvinen, HJ .
INTERNATIONAL JOURNAL OF CANCER, 1995, 64 (06) :430-433
[5]  
Bonaïti-Pellié C, 1999, EUR J CANCER PREV, V8, pS27
[6]  
Chapelle A, 1995, ANNU REV GENET, V29, P329
[7]  
Chompret A, 2000, BRIT J CANCER, V82, P1932
[8]   Recurrent germline mutation in MSH2 arises frequently de novo [J].
Desai, DC ;
Lockman, JC ;
Chadwick, RB ;
Gao, X ;
Percesepe, A ;
Evans, DGR ;
Miyaki, M ;
Yuen, ST ;
Radice, P ;
Maher, ER ;
Wright, FA ;
de la Chapelle, A .
JOURNAL OF MEDICAL GENETICS, 2000, 37 (09) :646-652
[9]   Cancer risk associated with germline DNA mismatch repair gene mutations [J].
Dunlop, MG ;
Farrington, SM ;
Carothers, AD ;
Wyllie, AH ;
Sharp, L ;
Burn, J ;
Liu, B ;
Kinzler, KW ;
Vogelstein, B .
HUMAN MOLECULAR GENETICS, 1997, 6 (01) :105-110
[10]   Breast cancer genes - What are the real risks? [J].
Easton, D .
NATURE GENETICS, 1997, 16 (03) :210-211