DECADE IN REVIEW-DYSLIPIDAEMIA Resurgence of targets and compounds to treat dyslipidaemia

被引：7

作者：

Kastelein, John J. P. ^{[1
]}

机构：

[1] Univ Amsterdam, Acad Med Ctr, Dept Vasc Med, NL-1105 AZ Amsterdam, Netherlands

来源：

NATURE REVIEWS CARDIOLOGY | 2014年 / 11卷 / 11期

关键词：

RISK; TRIGLYCERIDES;

D O I：

10.1038/nrcardio.2014.132

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Over the past decade, we have witnessed the unparalleled success of statins to treat dyslipidaemia. Target identification by Mendelian randomization, human monoclonal antibodies, gene therapy, RNA-based targets, and atherogenic lipoproteins other than LDL cholesterol have fuelled intense development efforts that might bear fruit in the very near future.

引用

页码：629 / 631

页数：3

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