Wide Field Super-Resolution Surface Imaging through Plasmonic Structured Illumination Microscopy

被引:141
作者
Wei, Feifei [1 ]
Lu, Dylan [1 ]
Shen, Hao [1 ]
Wan, Weiwei [1 ]
Ponsetto, Joseph Louis [1 ]
Huang, Eric [1 ]
Liu, Zhaowei [1 ,2 ]
机构
[1] Univ Calif San Diego, Dept Elect & Comp Engn, La Jolla, CA 92093 USA
[2] Univ Calif San Diego, Mat Sci & Engn Program, La Jolla, CA 92093 USA
基金
美国国家科学基金会;
关键词
Plasmonics; surface plasmon interference; structured illumination microscopy; super-resolution microscopy; OPTICAL RECONSTRUCTION MICROSCOPY; FLUORESCENCE MICROSCOPY; DIFFRACTION-LIMIT; INTERFERENCE NANOLITHOGRAPHY; EXCITATION MICROSCOPY; STIMULATED-EMISSION; VISIBLE WAVELENGTHS; RESOLUTION LIMIT; HYPERLENS; SUPERLENS;
D O I
10.1021/nl501695c
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
We experimentally demonstrate a wide field surface plasmon (SP) assisted super-resolution imaging technique, plasmonic structured illumination microscopy (PSIM), by combining tunable SP interference (SPI) with structured illumination microscopy (SIM). By replacing the laser interference fringes in conventional SIM with SPI patterns, PSIM exhibits greatly enhanced resolving power thanks to the unique properties of SP waves. This PSIM technique is a wide field, surface super-resolution imaging technique with potential applications in the field of high-speed biomedical imaging.
引用
收藏
页码:4634 / 4639
页数:6
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