Infantile anti-MuSK positive myasthenia gravis in a patient with autoimmune polyendocrinopathy type 3

被引：3

作者：

Duman, Ozgur ^{[1
]}

Koken, Resit ^{[1
]}

Baran, R. Taner ^{[2
]}

Haspolat, Senay ^{[1
]}

Topaloglu, Haluk ^{[3
]}

机构：

[1] Akdeniz Univ Hosp, Dept Pediat Neurol, Antalya, Turkey

[2] Akdeniz Univ Hosp, Dept Pediat Endocrinol, Antalya, Turkey

[3] Hacettepe Univ, Childrens Hosp, Dept Pediat Neurol, Ankara, Turkey

来源：

EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY | 2014年 / 18卷 / 04期

关键词：

Myasthenia gravis; Infant; MuSK; Autoimmune; Polyglandular syndromes;

D O I：

10.1016/j.ejpn.2014.02.006

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Myasthenia gravis (MG) is an autoimmune disorder caused by autoantibodies and related to the muscle nicotinic acetylcholine receptor (AChR) or muscle-specific tyrosine kinase (MuSK). Myasthenia gravis with anti-MuSK antibodies rarely occurs in children. The present article reports a childhood onset case of auto-immune MG with anti-MuSK antibodies, part of autoimmune polyglandular syndrome. (C) 2014 European Paediatric Neurology Society. Published by Elsevier Ltd. All rights reserved.

引用

页码：526 / 528

页数：3

共 13 条

[1] Vitiligo associated with other autoimmune diseases: polyglandular autoimmune syndrome types 3B+C and 4
Amerio, P.
Tracanna, M.
De Remigis, P.
Betterle, C.
Vianale, L.
Marra, M. E.
Di Rollo, D.
Capizzi, R.
Feliciani, C.
Tulli, A.
[J]. CLINICAL AND EXPERIMENTAL DERMATOLOGY, 2006, 31 (05) : 746 - 749
[2] Long Remission in Muscle-Specific Kinase Antibody-Positive Juvenile Myasthenia
Anlar, Banu
Yilmaz, Vuslat
Saruhan-Direskeneli, Gueher
[J]. PEDIATRIC NEUROLOGY, 2009, 40 (06) : 455 - 456
[3] Autoimmune adrenal insufficiency and autoimmune polyendocrine syndromes: Autoantibodies, autoantigens, and their applicability in diagnosis and disease prediction
Betterle, C
Dal Pra, C
Mantero, F
Zanchetta, R
[J]. ENDOCRINE REVIEWS, 2002, 23 (03) : 327 - 364
[4] Clinical correlates with anti-MuSK antibodies in generalized seronegative myasthenia gravis
Evoli, A
Tonali, PA
Padua, L
Lo Monaco, M
Scuderi, F
Batocchi, AP
Marino, M
Bartoccioni, E
[J]. BRAIN, 2003, 126 : 2304 - 2311
[5] MRI and clinical studies of facial and bulbar muscle involvement in MUSK antibody-associated myasthenia gravis
Farrugia, Maria Elena
Robson, Matthew D.
Clover, Linda
Anslow, Phil
Newsom-Davis, John
Kennett, Robin
Hilton-Jones, David
Matthews, Paul M.
Vincent, Angela
[J]. BRAIN, 2006, 129 : 1481 - 1492
[6] Antibody effector mechanisms in myasthenia gravis-Pathogenesis at the neuromuscular junction
Gomez, Alejandro M.
Van den Broeck, Joost
Vrolix, Kathleen
Janssen, Sofie P.
Lemmens, Marijke A. M.
Van der Esch, Eline
Duimel, Hans
Frederik, Peter
Molenaar, Peter C.
Martinez-Martinez, Pilar
De Baets, Marc H.
Losen, Mario
[J]. AUTOIMMUNITY, 2010, 43 (5-6) : 353 - 370
[7] Clinical characteristics of MuSK antibody-positive myasthenia gravis in Taiwan
Huang, Yung-Chuan
Yeh, Jiann-Horng
Chiu, Hou-Chang
Chen, Wei-Hung
[J]. JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION, 2008, 107 (07) : 572 - 575
[8] Autoimmune myasthenia gravis: emerging clinical and biological heterogeneity
Meriggioli, Matthew N.
Sanders, Donald B.
[J]. LANCET NEUROLOGY, 2009, 8 (05) : 475 - 490
[9] CLINICAL FINDINGS IN MuSK-ANTIBODY POSITIVE MYASTHENIA GRAVIS: A US EXPERIENCE
Pasnoor, Mamatha
Wolfe, Gil I.
Nations, Sharon
Trivedi, Jaya
Barohn, Richard J.
Herbelin, Laura
McVey, April
Dimachkie, Mazen
Kissel, John
Walsh, Ronan
Amato, Anthony
Mozaffar, Tahseen
Hungs, Marcel
Chui, Luis
Goldstein, Jonathan
Novella, Steven
Burns, Ted
Phillips, Lawrence
Claussen, Gwendolyn
Young, Angela
Bertorini, Tulio
Oh, Shin
[J]. MUSCLE & NERVE, 2010, 41 (03) : 370 - 374
[10] AChR phosphorylation and indirect inhibition of AChR function in seronegative MG
Plested, CP
Tang, T
Spreadbury, I
Littleton, ET
Kishore, U
Vincent, A
[J]. NEUROLOGY, 2002, 59 (11) : 1682 - 1688

← 1 2 →