Systemic and intraocular factors related to retinal thicknesses variations in patients with Parkinson's disease

被引：5

作者：

Desideri, Lorenzo Ferro ^{[1
]}

Barra, Fabio ^{[1
,2
]}

Ferrero, Simone ^{[1
,2
]}

机构：

[1] Univ Genoa, Dept Neurosci Rehabil Ophthalmol Genet Maternal &, Genoa, Italy

[2] IRCCS Osped Policlin San Martino, Acad Unit Obstet & Gynecol, Largo R Benzi 10, I-16132 Genoa, Italy

来源：

PARKINSONISM & RELATED DISORDERS | 2019年 / 61卷

关键词：

OCT; SD-OCT; Parkinson's disease; Retina; Retinal nerve fiber layer;

D O I：

10.1016/j.parkreldis.2018.11.004

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Parkinson's disease (PD) is characterized by a neurodegenerative process, which has been previously reported to involve some retinal layers, in particular the peripapillary retinal nerve fiber layer (RNFL) and macular ganglion cell complex (mGCC). When measuring pRNFL and mGCC by Optical Coherence Tomography in PD patients, it should not be neglected the role of possible both sistemic and intraocular factors, which have been proven to modify intraretinal thicknesses measurements. Nonetheless, also dopaminergic drugs administration could represent another important confounding factor, given their neuroprotective effect exerted on retina.

引用

页码：234 / 235

页数：2

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