共 99 条
Intrauterine transfusion and non-invasive treatment options for hemolytic disease of the fetus and newborn - review on current management and outcome
被引:72
作者:

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van Kamp, Inge
论文数: 0 引用数: 0
h-index: 0
机构:
Leiden Univ, Med Ctr, Dept Obstet, POB 9600, NL-2300 RC Leiden, Netherlands Leiden Univ, Med Ctr, Dept Obstet, POB 9600, NL-2300 RC Leiden, Netherlands

Oepkes, Dick
论文数: 0 引用数: 0
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Leiden Univ, Med Ctr, Dept Obstet, POB 9600, NL-2300 RC Leiden, Netherlands Leiden Univ, Med Ctr, Dept Obstet, POB 9600, NL-2300 RC Leiden, Netherlands

Lopriore, Enrico
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h-index: 0
机构:
Leiden Univ, Med Ctr, Dept Pediat, Div Neonatol, Leiden, Netherlands Leiden Univ, Med Ctr, Dept Obstet, POB 9600, NL-2300 RC Leiden, Netherlands
机构:
[1] Leiden Univ, Med Ctr, Dept Obstet, POB 9600, NL-2300 RC Leiden, Netherlands
[2] Leiden Univ, Med Ctr, Dept Pediat, Div Neonatol, Leiden, Netherlands
关键词:
Fetal anemia;
fetal therapy;
hemolytic disease of the fetus and newborn;
intrauterine blood transfusion;
intravenous immunoglobulin;
therapeutic plasma exchange and red cell alloimmunization in pregnancy;
RED-CELL ALLOIMMUNIZATION;
DOSE INTRAVENOUS IMMUNOGLOBULIN;
SEVERE ERYTHROBLASTOSIS-FETALIS;
PROCEDURE-RELATED COMPLICATIONS;
SEVERE RHESUS ISOIMMUNIZATION;
RH D-ALLOIMMUNIZATION;
ANTI-D CONCENTRATIONS;
INTRAVASCULAR TRANSFUSIONS;
GAMMA-GLOBULIN;
EXCHANGE-TRANSFUSION;
D O I:
10.1080/17474086.2017.1305265
中图分类号:
R5 [内科学];
学科分类号:
1002 ;
100201 ;
摘要:
Introduction: Hemolytic disease of the fetus and newborn (HDFN) remains a serious pregnancy complication which can lead to severe fetal anemia, hydrops and perinatal death.Areas covered: This review focusses on the current prenatal management, treatment with intrauterine transfusion (IUT) and promising non-invasive treatment options for HDFN.Expert commentary: IUTs are the cornerstone in prenatal management of HDFN and have significantly improved perinatal outcome in the past decades. IUT is now a relatively safe procedure, however the risk of complications is still high when performed early in the second trimester. Non-invasive management using intravenous immunoglobulin may be a safe alternative and requires further investigation.
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页码:337 / 344
页数:8
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