Interstitial cystitis and bladder mastocytosis in a woman with chronic urticaria

被引：7
作者：
Sant, GR
Theoharides, TC
Letourneau, R
Gelfand, J
机构：
[1] TUFTS UNIV,NEW ENGLAND MED CTR HOSP,SCH MED,DEPT PHARMACOL,BOSTON,MA 02111
[2] TUFTS UNIV,NEW ENGLAND MED CTR HOSP,SCH MED,DEPT MED,BOSTON,MA 02111
来源：
SCANDINAVIAN JOURNAL OF UROLOGY AND NEPHROLOGY | 1997年 / 31卷 / 05期
关键词：
D O I：
10.3109/00365599709030650
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
A patient with chronic urticaria and angioedema developed endoscopically confirmed interstitial cystitis. Bladder biopsy revealed bladder mastocytosis with >60 mast cells/mm(2) (normal <10) in the detrusor and submucosa. Most of the mast cells were activated and degranulated. The occurrence of IC in a patient with urticaria and angioedema, diseases both associated with mast cell pathophysiology, supports the role of mast cells in interstitial cystitis.
引用
收藏
页码：497 / 500
页数：4
相关论文
共 15 条
[1]   URTICARIAL VASCULITIS PROGRESSING TO SYSTEMIC LUPUS-ERYTHEMATOSUS [J].
BISACCIA, E ;
ADAMO, V ;
ROZAN, SW .
ARCHIVES OF DERMATOLOGY, 1988, 124 (07) :1088-1090
[2]   ELEVATED MAST-CELL TRYPTASE IN THE URINE OF PATIENTS WITH INTERSTITIAL CYSTITIS [J].
BOUCHER, W ;
ELMANSOURY, M ;
PANG, X ;
SANT, GR ;
THEOHARIDES, TC .
BRITISH JOURNAL OF UROLOGY, 1995, 76 (01) :94-100
[3]   INCREASED URINE HISTAMINE AND METHYLHISTAMINE IN INTERSTITIAL CYSTITIS [J].
ELMANSOURY, M ;
BOUCHER, W ;
SANT, GR ;
THEOHARIDES, TC .
JOURNAL OF UROLOGY, 1994, 152 (02) :350-353
[4]   CURRENT CONCEPTS - CHRONIC URTICARIA [J].
GREAVES, MW .
NEW ENGLAND JOURNAL OF MEDICINE, 1995, 332 (26) :1767-1772
[5]   AUTOANTIBODIES AGAINST THE HIGH-AFFINITY IGE RECEPTOR AS A CAUSE OF HISTAMINE-RELEASE IN CHRONIC URTICARIA [J].
HIDE, M ;
FRANCIS, DM ;
GRATTAN, CEH ;
HAKIMI, J ;
KOCHAN, JP ;
GREAVES, MW .
NEW ENGLAND JOURNAL OF MEDICINE, 1993, 328 (22) :1599-1604
[6]   CHRONIC IDIOPATHIC URTICARIA - PROFILES OF SKIN MAST-CELL HISTAMINE-RELEASE DURING ACTIVE DISEASE AND REMISSION [J].
JACQUES, P ;
LAVOIE, A ;
BEDARD, PM ;
BRUNET, C ;
HEBERT, J .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1992, 89 (06) :1139-1143
[7]  
KAUFMAN A, 1990, ANN ALLERGY, V65, P367
[8]   Intragranular activation of bladder mast cells and their association with nerve processes in interstitial cystitis [J].
Letourneau, R ;
Pang, X ;
Sant, GR ;
Theoharides, TC .
BRITISH JOURNAL OF UROLOGY, 1996, 77 (01) :41-54
[9]   BLADDER MAST-CELL EXPRESSION OF HIGH-AFFINITY ESTROGEN-RECEPTORS IN PATIENTS WITH INTERSTITIAL CYSTITIS [J].
PANG, X ;
COTREAUBIBBO, MM ;
SANT, GR ;
THEOHARIDES, TC .
BRITISH JOURNAL OF UROLOGY, 1995, 75 (02) :154-161
[10]  
SANT GR, 1994, UROL CLIN N AM, V21, P41
12