Retinal neurogenesis

被引：63

作者：

Centanin, Lazaro ^{[1
]}

Wittbrodt, Joachim ^{[1
]}

机构：

[1] Ctr Organismal Studies COS Heidelberg, Dept Dev Biol Physiol, D-69120 Heidelberg, Germany

来源：

DEVELOPMENT | 2014年 / 141卷 / 02期

关键词：

Neural progenitor cell; Neurogenesis; Retina; INTERKINETIC NUCLEAR MIGRATION; CELL-FATE DETERMINATION; STEM-CELLS; VERTEBRATE RETINA; PHOTORECEPTOR PRECURSORS; ZEBRAFISH RETINA; CLONAL ANALYSIS; MULLER GLIA; TRANSPLANTATION; PROGENITORS;

D O I：

10.1242/dev.083642

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

A unique feature of humans is the complexity of our central nervous system. A fully functional brain requires that billions of neurons make specific contacts in a highly coordinated way, an issue that is still not well understood. The neural retina constitutes an excellent system with which to analyze key aspects of neurogenesis and circuit formation in the central nervous system. Here, we provide an overview of retinal neurogenesis in vertebrates and discuss implications of the developmental mechanisms involved for regenerative therapy approaches.

引用

页码：241 / 244

页数：4

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