Anti-TNF alpha in the treatment of rheumatoid arthritis and ankylosing spondylitis

被引：6

作者：

Lanfant-Weybel, Karine ^{[1
]}

Lequerre, Thierry ^{[1
]}

Vittecoq, Olivier ^{[1
]}

机构：

[1] Hop Rouen, CHU Rouen, Serv Rhumatol, INSERM 905, F-76031 Rouen, France

来源：

PRESSE MEDICALE | 2009年 / 38卷 / 05期

关键词：

ANTITUMOR-NECROSIS-FACTOR; PLACEBO-CONTROLLED TRIAL; MAJOR CLINICAL-RESPONSE; DOUBLE-BLIND; PSORIATIC-ARTHRITIS; PLUS METHOTREXATE; INFLIXIMAB; THERAPY; ETANERCEPT; MULTICENTER;

D O I：

10.1016/j.lpm.2009.02.003

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Rheumatoid arthritis (RA) and ankylosing spondylitis (AS) ore, with psoriatic arthritis, the most frequent rheumatic diseases. A better understanding of pathophysiology of these diseases had led to the development of new treatments refered os to biologic agents and, among them, TNF blocking agents have a major role. The knowledge of these drugs in terms of mechanisms of action, indications and potentials side effects has to be known to improve the efficacy/tolerance balance. Although these 3 anti-TNF alpha agents are currently used, new TNF blocking agents ore under evaluation and should increase the number of drugs available within the next months

引用

页码：774 / 787

页数：14

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