Detection of Epstein-Barr virus in saliva by real-time PCR

被引：45
作者：
Idesawa, M
Sugano, N
Ikeda, K
Oshikawa, M
Takane, M
Seki, K
Ito, K
机构：
[1] Nihon Univ, Sch Dent, Dent Res Ctr,Div Adv Dent Treatment, Dept Periodontol,Chiyoda Ku, Tokyo 1018310, Japan
[2] Nihon Univ, Sch Dent, Grad Sch Dent, Tokyo 101, Japan
来源：
ORAL MICROBIOLOGY AND IMMUNOLOGY | 2004年 / 19卷 / 04期
关键词：
Epstein-Barr virus; periodontal treatment; real-time PCR; saliva;
D O I：
10.1111/j.1399-302X.2004.00144.x
中图分类号：
R78 [口腔科学];
学科分类号：
1003 ;
摘要：
The purpose of this investigation was to assess the salivary levels of Epstein-Barr virus (EBV) in patients with periodontitis using real-time PCR. EBV was detected in 16 out of 33 (48.5%) periodontitis patients and in 3 out of 20(15%) healthy subjects. The baseline mean values for bleeding on probing in EBV-positive patients were significantly higher than those in EBV-negative patients. A significant decrease in EBV levels was observed after initial periodontal treatment. Our findings indicate that levels of EBV in saliva may reflect the status of periodontal inflammation.
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收藏
页码：230 / 232
页数：3
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