Drug Burden Index in older adults: theoretical and practical issues

被引：113
作者：
Kouladjian, Lisa [1 ,2 ,3 ]
Gnjidic, Danijela [1 ,2 ,3 ,4 ]
Chen, Timothy F. [4 ]
Mangoni, Arduino A. [5 ,6 ]
Hilmer, Sarah N. [1 ,2 ,3 ]
机构：
[1] Univ Sydney, Kolling Inst Med Res, Sydney Med Sch, Sydney, NSW 2006, Australia
[2] Royal N Shore Hosp, Dept Clin Pharmacol, Sydney, NSW, Australia
[3] Royal N Shore Hosp, Dept Aged Care, Sydney, NSW, Australia
[4] Univ Sydney, Fac Pharm, Sydney, NSW 2006, Australia
[5] Flinders Univ S Australia, Sch Med, Dept Clin Pharmacol, Bedford Pk, SA 5042, Australia
[6] Flinders Med Ctr, Bedford Pk, SA, Australia
来源：
CLINICAL INTERVENTIONS IN AGING | 2014年 / 9卷
关键词：
Drug Burden Index; anticholinergics; sedative medications; high-risk prescribing; older adults; pharmacological risk assessment tools; deprescribing; DECISION-SUPPORT-SYSTEMS; POTENTIALLY INAPPROPRIATE MEDICATIONS; ANTICHOLINERGIC RISK SCALE; FUNCTIONAL BURDEN; PHYSICAL FUNCTION; APPROPRIATENESS INDEX; COGNITIVE FUNCTION; PEOPLE; POLYPHARMACY; ASSOCIATIONS;
D O I：
10.2147/CIA.S66660
中图分类号：
R592 [老年病学]; C [社会科学总论];
学科分类号：
03 ; 0303 ; 100203 ;
摘要：
Anticholinergic and sedative medications are commonly used in older adults and are associated with adverse clinical outcomes. The Drug Burden Index was developed to measure the cumulative exposure to these medications in older adults and its impact on physical and cognitive function. This narrative review discusses the research and clinical applications of the Drug Burden Index, and its advantages and limitations, compared with other pharmacologically developed measures of high-risk prescribing.
引用
收藏
页码：1503 / 1515
页数：13
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