A microfluidic flow chemistry platform for organic synthesis: the Hofmann rearrangement

被引：67
作者：
Palmieri, Alessandro [1 ]
Ley, Steven V. [1 ]
Hammond, Kelvin [2 ]
Polyzos, Anastasios [1 ,3 ]
Baxendale, Ian R. [1 ]
机构：
[1] Univ Cambridge, Dept Chem, ACS, Innovat Technol Ctr, Cambridge CB2 1EW, England
[2] Advion, Ithaca, NY 14850 USA
[3] CSIRO Mol & Hlth Technol, Melbourne, Vic 3169, Australia
来源：
TETRAHEDRON LETTERS | 2009年 / 50卷 / 26期
关键词：
POLYMER-SUPPORTED REAGENTS; THROUGH SYNTHESIS; REACTOR; CATALYSTS; MICROREACTOR; SCAVENGERS; BATCH; OPTIMIZATION;
D O I：
10.1016/j.tetlet.2009.02.059
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
We report on the use of commercially available chemical microreactors to effect the Hofmann rearrangement of aromatic amides to the corresponding carbamates. Crown Copyright (C) 2009 Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码：3287 / 3289
页数：3
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