Acute abducens nerve palsy in a patient with the novel coronavirus disease (COVID-19)

被引:70
作者
Falcone, Michelle M. [1 ]
Rong, Andrew J. [1 ]
Salazar, Humberto [1 ]
Redick, D. Wade [1 ]
Falcone, Steven [2 ]
Cavuoto, Kara M. [1 ]
机构
[1] Univ Miami, Miller Sch Med, Bascom Palmer Eye Inst, Miami, FL 33136 USA
[2] Univ Miami, Dept Radiol, Miller Sch Med, Miami, FL 33136 USA
来源
JOURNAL OF AAPOS | 2020年 / 24卷 / 04期
关键词
D O I
10.1016/j.jaapos.2020.06.001
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
We present a case of an abducens nerve palsy in a previously healthy young man in the setting of SARS-CoV-2 infection. Magnetic resonance imaging obtained 5 weeks after the onset of diplopia demonstrated an atrophic left lateral rectus muscle, which was hyperintense on T2 weighting, consistent with denervation. Although the mechanism of the nerve palsy remains unclear, it is suspected to be related to his viral illness, because the patient had no preexisting vascular risk factors or evidence of other neurologic disease on neuroimaging. Cranial nerve palsies may represent part of the neurologic spectrum of COVID-19.
引用
收藏
页码:216 / 217
页数:2
相关论文
共 14 条
[1]   Evidence of the COVID-19 Virus Targeting the CNS: Tissue Distribution, Host-Virus Interaction, and Proposed Neurotropic Mechanisms [J].
Baig, Abdul Mannan ;
Khaleeq, Areeba ;
Ali, Usman ;
Syeda, Hira .
ACS CHEMICAL NEUROSCIENCE, 2020, 11 (07) :995-998
[2]   Lateral Rectus Superior Compartment Palsy [J].
Clark, Robert A. ;
Demer, Joseph L. .
AMERICAN JOURNAL OF OPHTHALMOLOGY, 2014, 157 (02) :479-487
[3]   COVID-19 presenting with ophthalmoparesis from cranial nerve palsy [J].
Dinkin, Marc ;
Gao, Virginia ;
Kahan, Joshua ;
Bobker, Sarah ;
Simonetto, Marialaura ;
Wechsler, Paul ;
Harpe, Jasmin ;
Greer, Christine ;
Mints, Gregory ;
Salama, Gayle ;
Tsiouris, Apostolos John ;
Leifer, Dana .
NEUROLOGY, 2020, 95 (05) :221-223
[4]   Isolated Abducens Nerve Palsy: Update on Evaluation and Diagnosis [J].
Elder, Christopher ;
Hainline, Clotilde ;
Galetta, Steven L. ;
Balcer, Laura J. ;
Rucker, Janet C. .
CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS, 2016, 16 (08)
[5]   DENERVATED HUMAN SKELETAL-MUSCLE - MR IMAGING EVALUATION [J].
FLECKENSTEIN, JL ;
WATUMULL, D ;
CONNER, KE ;
EZAKI, M ;
GREENLEE, RG ;
BRYAN, WW ;
CHASON, DP ;
PARKEY, RW ;
PESHOCK, RM ;
PURDY, PD .
RADIOLOGY, 1993, 187 (01) :213-218
[6]   Miller Fisher syndrome and polyneuritis cranialis in COVID-19 [J].
Gutierrez-Ortiz, Consuelo ;
Mendez-Guerrero, Antonio ;
Rodrigo-Rey, Sara ;
San Pedro-Murillo, Eduardo ;
Bermejo-Guerrero, Laura ;
Gordo-Manas, Ricardo ;
de Aragon-Gomez, Fernando ;
Benito-Leon, Julian .
NEUROLOGY, 2020, 95 (05) :E601-E605
[7]   Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. A first step in understanding SARS pathogenesis [J].
Hamming, I ;
Timens, W ;
Bulthuis, MLC ;
Lely, AT ;
Navis, GJ ;
van Goor, H .
JOURNAL OF PATHOLOGY, 2004, 203 (02) :631-637
[8]   Comparison of orbital magnetic resonance imaging in Duane syndrome and abducens palsy [J].
Kang, Nam-Yeo ;
Demer, Joseph L. .
AMERICAN JOURNAL OF OPHTHALMOLOGY, 2006, 142 (05) :827-834
[9]   Sixth nerve palsies in children [J].
Lee, MS ;
Galetta, SL ;
Volpe, NJ ;
Liu, GT .
PEDIATRIC NEUROLOGY, 1999, 20 (01) :49-52
[10]   Neurologic Manifestations of Hospitalized Patients With Coronavirus Disease 2019 in Wuhan, China [J].
Mao, Ling ;
Jin, Huijuan ;
Wang, Mengdie ;
Hu, Yu ;
Chen, Shengcai ;
He, Quanwei ;
Chang, Jiang ;
Hong, Candong ;
Zhou, Yifan ;
Wang, David ;
Miao, Xiaoping ;
Li, Yanan ;
Hu, Bo .
JAMA NEUROLOGY, 2020, 77 (06) :683-690