A facile method for the solution and solid-phase synthesis of substituted [3.3.1] bicycles

被引：80
作者：
Nicolaou, KC
Pfefferkorn, JA
Cao, GQ
Kim, S
Kessabi, J
机构：
[1] Scripps Res Inst, Dept Chem, La Jolla, CA 92037 USA
[2] Scripps Res Inst, Skaggs Inst Chem Biol, La Jolla, CA 92037 USA
[3] Univ Calif San Diego, Dept Biochem & Chem, La Jolla, CA 92093 USA
来源：
ORGANIC LETTERS | 1999年 / 1卷 / 05期
关键词：
D O I：
10.1021/ol990791d
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
[GRAPHICS] Interest in bicyclic natural products from the Guttiferae classification has led to the development of an improved method for the selenium mediated cyclization of alkenyl-substituted beta-dicarbonyls (I) to form a variety of bicyclo[3.3.1]nonan-9-ones (II) both in solution and on solid support.
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页码：807 / 810
页数：4
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