Typical doses and dose rates in studies pertinent to radiation risk inference at low doses and low dose rates

被引:40
作者
Ruehm, Werner [1 ]
Azizova, Tamara [2 ]
Bouffler, Simon [3 ]
Cullings, Harry M. [4 ]
Grosche, Bernd [5 ]
Little, Mark P. [6 ]
Shore, Roy S. [7 ]
Walsh, Linda [8 ]
Woloschak, Gayle E. [9 ,10 ,11 ]
机构
[1] Helmholtz Zentrum Munchen, Inst Radiat Protect, Ingolstadter Landstr 1, D-85764 Neuherberg, Germany
[2] SUBI, Ozyorskoe Shosse 19, Ozyorsk 456780, Chelyabinsk Reg, Russia
[3] PHE, Ctr Radiat Chem & Environm Hazards, Didcot OX11 0RQ, Oxon, England
[4] Radiat Effects Res Fdn, Minami Ku, 5-2 Hijiyama Pk, Hiroshima 7320815, Japan
[5] Fed Off Radiat Protect, Ingolstadter Landstr 1, D-85764 Oberschleissheim, Germany
[6] NCI, Radiat Epidemiol Branch, Div Canc Epidemiol & Genet, 9609 Med Ctr Dr, Bethesda, MD 20892 USA
[7] NYU, Sch Med, 650 First Ave, New York, NY 10016 USA
[8] Univ Zurich, Sci Fac, Dept Phys, Med Phys Grp, Winterthurerstr 190, CH-8057 Zurich, Switzerland
[9] Northwestern Univ, Feinberg Sch Med, Robert H Lurie Comprehens Canc Ctr, Dept Radiat Oncol, 300 E Super St,Tarry 4-760, Chicago, IL 60611 USA
[10] Northwestern Univ, Feinberg Sch Med, Robert H Lurie Comprehens Canc Ctr, Dept Radiol, 300 E Super St,Tarry 4-760, Chicago, IL 60611 USA
[11] Northwestern Univ, Feinberg Sch Med, Robert H Lurie Comprehens Canc Ctr, Dept Cell & Mol Biol, 300 E Super St,Tarry 4-760, Chicago, IL 60611 USA
基金
美国国家卫生研究院;
关键词
radiation risk; ionizing radiation; low doses; low dose rates; SOLID CANCER INCIDENCE; ATOMIC-BOMB SURVIVORS; MAYAK WORKER DOSIMETRY; BACKGROUND-RADIATION; GAMMA-RAY; LIFE-SPAN; MORTALITY; EXPOSURE; HIROSHIMA; SYSTEM;
D O I
10.1093/jrr/rrx093
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
In order to quantify radiation risks at exposure scenarios relevant for radiation protection, often extrapolation of data obtained at high doses and high dose rates down to low doses and low dose rates is needed. Task Group TG91 on 'Radiation Risk Inference at Low-dose and Low-dose Rate Exposure for Radiological Protection Purposes' of the International Commission on Radiological Protection is currently reviewing the relevant cellular, animal and human studies that could be used for that purpose. This paper provides an overview of dose rates and doses typically used or present in those studies, and compares them with doses and dose rates typical of those received by the A-bomb survivors in Japan.
引用
收藏
页码:ii1 / ii10
页数:10
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