Virilization in a Girl Caused by an Ovarian Yolk Sac Tumor: A Case Report

被引：2

作者：

Yang, Min ^{[1
]}

Xin, Ying ^{[1
]}

机构：

[1] China Med Univ, Shengjing Hosp, Dept Pediat, 36 Sanhao St, Shenyang 110004, Liaoning, Peoples R China

来源：

JOURNAL OF PEDIATRIC AND ADOLESCENT GYNECOLOGY | 2019年 / 32卷 / 03期

关键词：

Virilization; Yolk sac tumor; Leydig cells; CELLS;

D O I：

10.1016/j.jpag.2019.01.001

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Background: Yolk sac tumors (YSTs) are rare malignancies that originate from germ cells and rarely present with endocrine symptoms. We report a case of a 13-year-old girl with a YST manifesting as virilization. Case: A 13-year-old girl was diagnosed with a YST with endocrine symptoms because of Leydig cells in the stroma, which were identified using hematoxylin and eosin staining and immunohistochemistry. Summary and Conclusion: This case suggests that clinicians should consider the possibility of YST when encountering patients with symptoms of virilization. When a YST is found to have endocrine function, a functioning stroma could present. Immunohistochemistry is useful for identifying stromal cells and performing a differential diagnosis.

引用

页码：330 / 333

页数：4

共 8 条

[1] Ovarian yolk sac tumor with virilization during pregnancy: Immunohistochemical demonstration of Leydig cells as functioning stroma [J].