Relationship Between Hematologic Indices and Global Registry of Acute Coronary Events Risk Score in Patients With ST-Segment Elevation Myocardial Infarction

被引：58

作者：

Acet, Halit ^{[1
]}

Ertas, Faruk ^{[1
]}

Akil, Mehmet Ata ^{[1
]}

Ozyurtlu, Ferhat ^{[2
]}

Polat, Nihat ^{[1
]}

Bilik, Mehmet Zihni ^{[1
]}

Aydin, Mesut ^{[1
]}

Oylumlu, Mustafa ^{[1
]}

Yuksel, Murat ^{[1
]}

Yildiz, Abdulkadir ^{[1
]}

Kaya, Hasan ^{[1
]}

Akyuz, Abdurrahman ^{[1
]}

Ozbek, Mehmet ^{[1
]}

机构：

[1] Dicle Univ, Fac Med, Dept Cardiol, Diyarbakir, Turkey

[2] Izmir Univ, Fac Med, Dept Cardiol, Izmir, Turkey

来源：

CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS | 2016年 / 22卷 / 01期

关键词：

GRACE risk score; hematologic indices; STEMI; platelet to lymphocyte ratio; neutrophil to lymphocyte ratio; CELL DISTRIBUTION WIDTH; LONG-TERM MORTALITY; LYMPHOCYTE RATIO; INFLAMMATORY BIOMARKERS; PROGNOSTIC MARKER; HEART-FAILURE; NEUTROPHIL; PLATELET; DISEASE; PREDICTORS;

D O I：

10.1177/1076029614533145

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The aim of this study was to evaluate the relationship between hematologic indices and the Global Registry of Acute Coronary Events (GRACE) score in patients with ST-segment elevation myocardial infarction (STEMI). A total of 800 patients who consecutively and retrospectively presented with STEMI within 12 hours of symptom onset. After accounting for exclusion criteria, a total of 379 patients remained in the study. We enrolled 379 patients with STEMI (mean age 61.7 +/- 13.6 years; men 73%). Neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), red cell distribution width (RDW), and monocyte count were associated with increased worse GRACE risk score (P = .008, P = .012, P = .005, P = .022, respectively). In multivariate linear regression analysis, NLR, PLR, RDW, and monocyte count were found to be independent predictors of GRACE risk score. We demonstrate for the first time that PLR, RDW, and monocyte were associated with the GRACE score in patients with STEMI.

引用

页码：60 / 68

页数：9

共 60 条

[1] The Relation of Platelet-Lymphocyte Ratio and Coronary Collateral Circulation in Patients With Stable Angina Pectoris and Chronic Total Occlusion [J].

Acar, Goeksel ;

Kalkan, Mehmet Emin ;

Avci, Anil ;

Alizade, Elnur ;

Tabakci, Mehmet Mustafa ;

Toprak, Cuneyt ;

Ozkan, Birol ;

Alici, Gokhan ;

Esen, Ali Metin .

CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS, 2015, 21 (05) :462-468

[2] New inflammatory predictors for non-valvular atrial fibrillation: echocardiographic epicardial fat thickness and neutrophil to lymphocyte ratio [J].

Acet, Halit ;

Ertas, Faruk ;

Akil, Mehmet Ata ;

Oylumlu, Mustafa ;

Polat, Nihat ;

Yildiz, Abdulkadir ;

Bilik, Mehmet Zihni ;

Yuksel, Murat ;

Kaya, Zeynettin ;

Ulgen, Mehmet Siddik .

INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING, 2014, 30 (01) :81-89

[3] Relation of Neutrophil/Lymphocyte Ratio to Coronary Flow to In-Hospital Major Adverse Cardiac Events in Patients With ST-Elevated Myocardial Infarction Undergoing Primary Coronary Intervention [J].

Akpek, Mahmut ;

Kaya, Mehmet Gungor ;

Lam, Yat Yin ;

Sahin, Omer ;

Elcik, Deniz ;

Celik, Turgay ;

Ergin, Ali ;

Gibson, Charles Michael .

AMERICAN JOURNAL OF CARDIOLOGY, 2012, 110 (05) :621-627

[4] Myocardial infarction redefined -: A consensus document of the Joint European Society of Cardiology/American College of Cardiology Committee for the Redefinition of Myocardial Infarction [J].

Alpert, JS ;

Antman, E ;

Apple, F ;

Armstrong, PW ;

Bassand, JP ;

de Luna, AB ;

Beller, G ;

Breithardt, G ;

Chaitman, BR ;

Clemmensen, P ;

Falk, E ;

Fishbein, MC ;

Galvani, M ;

Garson, A ;

Grines, C ;

Hamm, C ;

Hoppe, U ;

Jaffe, A ;

Katus, H ;

Kjekshus, J ;

Klein, W ;

Klootwijk, P ;

Lenfant, C ;

Levy, D ;

Levy, RI ;

Luepker, R ;

Marcus, F ;

Näslund, U ;

Ohman, M ;

Pahlm, O ;

Poole-Wilson, P ;

Popp, R ;

Pyörälä, K ;

Ravkilde, J ;

Rehnquist, N ;

Roberts, W ;

Roberts, R ;

Roelandt, J ;

Rydén, L ;

Sans, S ;

Simoons, ML ;

Thygesen, K ;

Tunstall-Pedoe, H ;

Underwood, R ;

Uretsky, BF ;

de Werf, FV ;

Voipio-Pulkki, LM ;

Wagner, G ;

Wallentin, L ;

Wijns, W .

EUROPEAN HEART JOURNAL, 2000, 21 (18) :1502-1513

[5] Neutrophil count and infarct size in patients with acute myocardial infarction [J].

Avanzas, P ;

Quiles, J ;

de Sá, EL ;

Sánchez, A ;

Rubio, R ;

García, E ;

López-Sendón, JL .

INTERNATIONAL JOURNAL OF CARDIOLOGY, 2004, 97 (01) :155-156

[6] Value of platelet/lymphocyte ratio as a predictor of all-cause mortality after non-ST-elevation myocardial infarction [J].

Azab, Basem ;

Shah, Neeraj ;

Akerman, Meredith ;

McGinn, Joseph T., Jr. .

JOURNAL OF THROMBOSIS AND THROMBOLYSIS, 2012, 34 (03) :326-334

[7] Usefulness of Neutrophil to Lymphocyte Ratio in Predicting Short- and Long-Term Mortality After Non-ST-Elevation Myocardial Infarction [J].

Azab, Basem ;

Zaher, Medhat ;

Weiserbs, Kera F. ;

Torbey, Estelle ;

Lacossiere, Kenson ;

Gaddam, Sainath ;

Gobunsuy, Romel ;

Jadonath, Sunil ;

Baldari, Duccio ;

McCord, Donald ;

Lafferty, James .

AMERICAN JOURNAL OF CARDIOLOGY, 2010, 106 (04) :470-476

[8]

Barisione C, 2010, DIS MARKERS, V28, P115, DOI [10.1155/2010/236405, 10.3233/DMA-2010-0691]

[9] Preoperative hematologic markers as independent predictors of prognosis in resected pancreatic ductal adenocarcinoma: neutrophil-lymphocyte versus platelet-lymphocyte ratio [J].

Bhatti, Imran ;

Peacock, Oliver ;

Lloyd, Gareth ;

Larvin, Michael ;

Hall, Richard I. .

AMERICAN JOURNAL OF SURGERY, 2010, 200 (02) :197-203

[10] Relation between red blood cell distribution width (RDW) and all-cause mortality at two years in an unselected population referred for coronary angiography [J].

Cavusoglu, Erdal ;

Chopra, Vineet ;

Gupta, Amit ;

Battala, Venkata R. ;

Poludasu, Shyam ;

Eng, Calvin ;

Marmur, Jonathan D. .

INTERNATIONAL JOURNAL OF CARDIOLOGY, 2010, 141 (02) :141-146

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