Atypical teratoid/rhabdoid tumour with leptomeningeal dissemination in an adult

被引：30

作者：

Kawaguchi, T

Kumabe, T

Watanabe, M

Tominaga, T

机构：

[1] Tohoku Univ, Grad Sch Med, Dept Neurosurg, Aoba Ku, Sendai, Miyagi 9808574, Japan

[2] Tohoku Univ, Grad Sch Med, Dept Pathol, Sendai, Miyagi 980, Japan

来源：

ACTA NEUROCHIRURGICA | 2004年 / 146卷 / 09期

关键词：

atypical teratoid/rhabdoid tumour; chemotherapy; leptomeningeal dissemination; radiation;

D O I：

10.1007/s00701-004-0313-5

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

A 22-year-old man presented with a rare case of atypical teratoid/rhabdoid tumour (AT/RT). Magnetic resonance imaging showed a left cerebellar mass with leptomeningeal dissemination. Partial resection was performed. Histological examination revealed AT/RT. Postoperatively, whole neuraxis and local irradiation were performed. Three-drug chemotherapy with ifosfamide, cisplatin, and etoposide, and adjuvant intrathecal administration of methotrexate were repeated. Near complete response was achieved, and no tumour recurrence/progression has been noticed during the follow up of 24 months. Intensive radiochemotherapy can successfully control AT/RT, even with leptomeningeal dissemination.

引用

页码：1033 / 1038

页数：6

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