TIS11 Family Proteins and Their Roles in Posttranscriptional Gene Regulation

被引：83
作者：
Baou, Maria [1 ,2 ]
Jewell, Andrew [3 ,4 ]
Murphy, John J. [1 ]
机构：
[1] Kings Coll London, Div Immunol Infect & Inflammatory Dis, London WC2R 2LS, England
[2] Univ Leicester, MRC, Toxicol Unit, Leicester LE1 7RH, Leics, England
[3] Kingston Univ, Fac Hlth & Social Care Sci, London SW17 0RE, England
[4] St George Hosp, Sch Med, London SW17 0RE, England
来源：
JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY | 2009年
关键词：
AU-RICH ELEMENT; ZINC-FINGER PROTEINS; MESSENGER-RNA DECAY; EARLY RESPONSE GENE; TETRADECANOYL PHORBOL ACETATE; KINASE-ACTIVATED PROTEIN-KINASE-2; LYMPHOCYTIC-LEUKEMIA CELLS; COLONY-STIMULATING FACTOR; TRISTETRAPROLIN FAMILY; BINDING-PROTEIN;
D O I：
10.1155/2009/634520
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Posttranscriptional regulation of gene expression of mRNAs containing adenine-uridine rich elements (AREs) in their 3' untranslated regions is mediated by a number of different proteins that interact with these elements to either stabilise or destabilise them. The present review concerns the TPA-inducible sequence 11 (TIS11) protein family, a small family of proteins, that appears to interact with ARE-containing mRNAs and promote their degradation. This family of proteins has been extensively studied in the past decade. Studies have focussed on determining their biochemical functions, identifying their target mRNAs, and determining their roles in cell functions and diseases. Copyright (C) 2009
引用
收藏
页数：11
相关论文
共 110 条
  • [1] Breast cancer molecular signatures as determined by SAGE: correlation with lymph node status
    Abba, Martin C.
    Sun, Hongxia
    Hawkins, Kathleen A.
    Drake, Jeffrey A.
    Hu, Yuhui
    Nunez, Maria I.
    Gaddis, Sally
    Shi, Tao
    Horvath, Steve
    Sahin, Aysegul
    Aldaz, C. Marcelo
    [J]. MOLECULAR CANCER RESEARCH, 2007, 5 (09) : 881 - 890
  • [2] A CYS3His zinc-binding domain from Nup475/Tristetraprolin:: A novel fold with a disklike structure
    Amann, BT
    Worthington, MT
    Berg, JM
    [J]. BIOCHEMISTRY, 2003, 42 (01) : 217 - 221
  • [3] MicroRNA targets in immune genes and the Dicer/Argonaute and ARE machinery components
    Asirvatham, Ananthi J.
    Gregorie, Christopher J.
    Hu, Zihua
    Magner, William J.
    Tomasi, Thomas B.
    [J]. MOLECULAR IMMUNOLOGY, 2008, 45 (07) : 1995 - 2006
  • [4] ARED 2.0: an update of AU-rich element mRNA database
    Bakheet, T
    Williams, BRG
    Khabar, KSA
    [J]. NUCLEIC ACIDS RESEARCH, 2003, 31 (01) : 421 - 423
  • [5] Involvement of Tis11b, an AU-rich binding protein, in induction of apoptosis by rituximab in B cell chronic lymphocytic leukemia cells
    Baou, M.
    Jewell, A.
    Muthurania, A.
    Wickremasinghe, R. G.
    Yong, K. L.
    Carr, R.
    Marsh, P.
    Murphy, J. J.
    [J]. LEUKEMIA, 2009, 23 (05) : 986 - 989
  • [6] The RNA binding protein Zfp36l1 is required for normal vascularisation and post-transcriptionally regulates VEGF expressiono
    Bell, Sarah E.
    Sanchez, Maria Jose
    Spasic-Boskovic, Olivera
    Santalucia, Tomas
    Gambardella, Laure
    Burton, Graham J.
    Murphy, John J.
    Norton, John D.
    Clark, Andrew R.
    Turner, Martin
    [J]. DEVELOPMENTAL DYNAMICS, 2006, 235 (11) : 3144 - 3155
  • [7] Tristetraprolin and other CCCH tandem zinc-finger proteins in the regulation of mRNA turnover
    Blackshear, PJ
    [J]. BIOCHEMICAL SOCIETY TRANSACTIONS, 2002, 30 : 945 - 952
  • [8] Zfp36l3, a rodent X chromosome gene encoding a placenta-specific member of the tristetraprolin family of CCCH tandem zinc finger proteins
    Blackshear, PJ
    Phillips, RS
    Ghosh, S
    Ramos, SVB
    Richfield, EK
    Lai, WS
    [J]. BIOLOGY OF REPRODUCTION, 2005, 73 (02) : 297 - 307
  • [9] Polymorphisms in the genes encoding members of the tristetraprolin family of human tandem CCCH zinc finger proteins
    Blackshear, PJ
    Phillips, RS
    Vazquez-Matias, J
    Mohrenweiser, H
    [J]. PROGRESS IN NUCLEIC ACID RESEARCH AND MOLECULAR BIOLOGY, VOL 75, 2003, 75 : 43 - 68
  • [10] Characteristics of the interaction of a synthetic human tristetraprolin tandem zinc finger peptide with AU-rich element-containing RNA substrates
    Blackshear, PJ
    Lai, WS
    Kennington, EA
    Brewer, G
    Wilson, GM
    Guan, XJ
    Zhou, P
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (22) : 19947 - 19955
12345678910