Thyroid receptor subtypes: Structure and function in fish

被引：64

作者：

Nelson, Erik R. ^{[1
]}

Habibi, Hamid R. ^{[1
]}

机构：

[1] Univ Calgary, Dept Biol Sci, Calgary, AB T2N 1N4, Canada

来源：

GENERAL AND COMPARATIVE ENDOCRINOLOGY | 2009年 / 161卷 / 01期

关键词：

Thyroid receptor; Deiodinase; Goldfish; Steroid; Estrogen; Estradiol; Testosterone; 11-ketotestosterone; Regulation; Liver; Gonad; Testis; Ovary; Gene expression; PROLIFERATOR-ACTIVATED RECEPTOR; RETINOIC ACID RECEPTOR; HORMONE RESPONSE ELEMENT; PEROXISOME PROLIFERATOR; CONGER-MYRIASTER; TRANSCRIPTIONAL ACTIVATION; IODOTHYRONINE DEIODINASES; DEOXYRIBONUCLEIC-ACID; SIGNALING PATHWAYS; LARVAL DEVELOPMENT;

D O I：

10.1016/j.ygcen.2008.09.006

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Thyroid hormones are important regulators of vertebrate growth and development, and are under the control of the hypothalamic-pituitary-thyroid axis. Nuclear thyroid receptors (TRs), which act as inducible transcription factors, mediate cellular functions of thyroid hormones. The molecular structure of several subtypes of TRs have been elucidated in vertebrate species, including N-terminal truncations as well as C-terminal variations in the domain responsible for binding hormone. in this paper, we review current information on the thyroid receptors studied in the vertebrate species with emphasison recent findings in goldfish concerning functional significance of the thyroid receptor subtypes. (c) 2008 Elsevier Inc. All rights reserved.

引用

页码：90 / 96

页数：7

共 78 条

[1] The N-CoR complex enables chromatin remodeler SNF2H to enhance repression by thyroid hormone receptor [J].

Alenghat, Theresa ;

Yu, Jiujiu ;

Lazar, Mitchell A. .

EMBO JOURNAL, 2006, 25 (17) :3966-3974

[2]

ARSAN O M, 1987, Zhurnal Evolyutsionnoi Biokhimii i Fiziologii, V23, P287

[3] Mechanisms of thyroid hormone receptor-specific nuclear and extra nuclear actions [J].

Bassett, JHD ;

Harvey, CB ;

Williams, GR .

MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2003, 213 (01) :1-11

[4] THE TYPE-III 5-DEIODINASE IN RANA-CATESBEIANA TADPOLES IS ENCODED BY A THYROID HORMONE-RESPONSIVE GENE [J].

BECKER, KB ;

SCHNEIDER, MJ ;

DAVEY, JC ;

GALTON, VA .

ENDOCRINOLOGY, 1995, 136 (10) :4424-4431

[5] HETERODIMERIZATION AMONG THYROID-HORMONE RECEPTOR, RETINOIC ACID RECEPTOR, RETINOID-X RECEPTOR, CHICKEN OVALBUMIN UPSTREAM PROMOTER TRANSCRIPTION FACTOR, AND AN ENDOGENOUS LIVER PROTEIN [J].

BERRODIN, TJ ;

MARKS, MS ;

OZATO, K ;

LINNEY, E ;

LAZAR, MA .

MOLECULAR ENDOCRINOLOGY, 1992, 6 (09) :1468-1478

[6] Biochemistry, cellular and molecular biology, and physiological roles of the iodothyronine selenodeiodinases [J].

Bianco, AC ;

Salvatore, D ;

Gereben, B ;

Berry, MJ ;

Larsen, PR .

ENDOCRINE REVIEWS, 2002, 23 (01) :38-89

[7] The hypothalamic-pituitary-thyroid (HPT) axis in fish and its role in fish development and reproduction [J].

Blanton, Michael L. ;

Specker, Jennifer L. .

CRITICAL REVIEWS IN TOXICOLOGY, 2007, 37 (1-2) :97-115

[8]

BOGAZZI F, 1994, J BIOL CHEM, V269, P11683

[9] A cDNA for a putative type III deiodinase in the trout (Oncorhynchus mykiss):: Influence of holding conditions and thyroid hormone treatment on its hepatic expression [J].

Bres, O ;

Plohman, JC ;

Eales, JG .

GENERAL AND COMPARATIVE ENDOCRINOLOGY, 2006, 145 (01) :92-100

[10]

BURNSIDE J, 1990, J BIOL CHEM, V265, P2500

← 1 2 3 4 5 6 7 8 →